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- Title
Influence of Sex and Sex-Based Disparities on Prevalent Tuberculosis, Vietnam, 2017–2018.
- Authors
Hai Viet Nguyen; Daniella Brals; Edine Tiemersma; Gasior, Robert; Nhung Viet Nguyen; Hoa Binh Nguyen; Hung Van Nguyen; Ngoc Anh Le Thi; Cobelens, Frank
- Abstract
To assess sex disparities in tuberculosis in Vietnam, we conducted a nested, case–control study based on a 2017 tuberculosis prevalence survey. We defined the case group as all survey participants with laboratory–confirmed tuberculosis and the control group as a randomly selected group of participants with no tuberculosis. We used structural equation modeling to describe pathways from sex to tuberculosis according to an a priori conceptual framework. Our analysis included 1,319 participants, of whom 250 were case-patients. We found that sex was directly associated with tuberculosis prevalence (adjusted odds ratio for men compared with women 3.0 [95% CI 1.7–5.0]) and indirectly associated through other domains. The strong sex difference in tuberculosis prevalence is explained by a complex interplay of factors relating to behavioral and environmental risks, access to healthcare, and clinical manifestations. However, after controlling for all those factors, a direct sex effect remains that might be caused by biological factors.
- Subjects
VIETNAM; TUBERCULOSIS; STRUCTURAL equation modeling; HEALTH services accessibility; SYMPTOMS
- Publication
Emerging Infectious Diseases, 2023, Vol 29, Issue 5, p967
- ISSN
1080-6040
- Publication type
Article
- DOI
10.3201/eid2905.221476