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- Title
Comparison of Sebia Capillarys 3-OCTA with the Tosoh Bioscience HLC<sup>®</sup>-723G8 method for A1C testing with focus on analytical interferences and variant detection.
- Authors
Dupuy, Anne Marie; Badiou, Stéphanie; Marrolley, Justine; Plawecki, Maelle; Aguilar-Martinez, Patricia; Cristol, Jean Paul
- Abstract
Comparison of the Sebia 3-OCTA vs. the Tosoh-G8 showed a strong correlation (r=0.995), with a bias of -0.1% (-1.4 mmol/mol) (Supplemental Material, Figure A). Keywords: analytical interferences; comparison method; hemoglobin variant; imprecision EN analytical interferences comparison method hemoglobin variant imprecision e216 e220 5 08/05/22 20220801 NES 220801 To the Editor, Great effort has been made to standardize the methods for the measurement of HbA SB 1c sb , however, analytical interferences persist with some HbA SB 1c sb methods in presence of hemoglobin (Hb) variants, high levels of HbF or uremia. Special attention should be given to the results of HbA SB 1c sb in the presence of HbA/G-San Jose on Sebia 3-OCTA and the presence of HbA/E and HbA/D-Punjab on the Tosoh G8. Comparison of Sebia Capillarys 3-OCTA with the Tosoh Bioscience HLC®-723G8 method for A1C testing with focus on analytical interferences and variant detection.
- Subjects
BLAND-Altman plot; LIFE sciences; HIGH performance liquid chromatography; FETAL hemoglobin
- Publication
Clinical Chemistry & Laboratory Medicine, 2022, Vol 60, Issue 9, pe216
- ISSN
1434-6621
- Publication type
Article
- DOI
10.1515/cclm-2022-0462