We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Ferritin, blood urea nitrogen, and high chest CT score determines ICU admission in COVID-19 positive UAE patients: A single center retrospective study.
- Authors
Bendardaf, Riyad; Bhamidimarri, Poorna Manasa; Al-Abadla, Zainab; Zein, Dima; Alkhayal, Noura; Georgy, Ramy Refaat; Al Ali, Feda; Elkhider, Alaa; Qadri, Sadeq; Hamoudi, Rifat; Abusnana, Salah
- Abstract
Coronavirus Disease (COVID-19) was declared a pandemic by WHO in March 2020. Since then, additional novel coronavirus variants have emerged challenging the current healthcare system worldwide. There is an increased need for hospital care, especially intensive care unit (ICU), for the patients severely affected by the disease. Most of the studies analyzed COVID-19 infected patients in the hospitals and established the positive correlation between clinical parameters such as high levels of D-dimer, C-reactive protein, and ferritin to the severity of infection. However, little is known about the course of the ICU admission. The retrospective study carried out at University Hospital Sharjah, UAE presented here reports an integrated analysis of the biochemical and radiological factors among the newly admitted COVID-19 patients to decide on their ICU admission. The descriptive statistical analysis revealed that patients with clinical presentations such as acute respiratory distress syndrome (ARDS) (p<0.0001) at the time of admission needed intensive care. The ROC plot indicated that radiological factors including high chest CT scores (>CO-RADS 4) in combination with biochemical parameters such as higher levels of blood urea nitrogen (>6.7 mg/dL;66% sensitivity and 75.8% specificity) and ferritin (>290 μg/mL, 71.4% sensitivity and 77.8% specificity) may predict ICU admission with 94.2% accuracy among COVID-19 patients. Collectively, these findings would benefit the hospitals to predict the ICU admission amongst COVID-19 infected patients.
- Subjects
SHARJAH (United Arab Emirates); INTENSIVE care units; COVID-19; BLOOD urea nitrogen; COMPUTED tomography; SARS-CoV-2; ADULT respiratory distress syndrome; FERRITIN
- Publication
PLoS ONE, 2022, Vol 17, Issue 7, p1
- ISSN
1932-6203
- Publication type
Article
- DOI
10.1371/journal.pone.0269185