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Demyelinating Diseases: From Molecular Mechanisms to Therapeutic Strategies.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 5, p. 4596, doi. 10.3390/ijms24054596
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Adaptive Response in Rat Retinal Cell Cultures Irradiated with γ-rays.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 3, p. 1972, doi. 10.3390/ijms24031972
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- Article
Repurposing Dipyridamole in Niemann Pick Type C Disease: A Proof of Concept Study.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 7, p. 3456, doi. 10.3390/ijms23073456
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- Article
The Antihypertensive Drug Telmisartan Protects Oligodendrocytes from Cholesterol Accumulation and Promotes Differentiation by a PPAR-γ-Mediated Mechanism.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 17, p. 9434, doi. 10.3390/ijms22179434
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Myelin Defects in Niemann–Pick Type C Disease: Mechanisms and Possible Therapeutic Perspectives.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 16, p. 8858, doi. 10.3390/ijms22168858
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- Article
Excessive Innate Immunity Steers Pathogenic Adaptive Immunity in the Development of Theiler's Virus-Induced Demyelinating Disease.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 10, p. 5254, doi. 10.3390/ijms22105254
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- Article
The Current Challenges for Drug Discovery in CNS Remyelination.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 6, p. 2891, doi. 10.3390/ijms22062891
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- Article
NRF2 and PPAR-γ Pathways in Oligodendrocyte Progenitors: Focus on ROS Protection, Mitochondrial Biogenesis and Promotion of Cell Differentiation.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 19, p. 7216, doi. 10.3390/ijms21197216
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- Article
Annamaria Cimini, Antonietta Bernardo, Maria Grazia Cifone, Luisa Di Marzio, Silvia Di Loreto. TNF downregulates PPAR expression in oligodendrocyte progenitor cells: Implications for demyelinating diseases. GLIA 2003;41(1):3-14.
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- Glia, 2003, v. 41, n. 2, p. 212, doi. 10.1002/glia.10199
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TNFα downregulates PPARδ expression in oligodendrocyte progenitor cells: Implications for demyelinating diseases.
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- Glia, 2003, v. 41, n. 1, p. 3, doi. 10.1002/glia.10143
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- Article
Astrocytes contribute to neuronal impairment in βA toxicity increasing apoptosis in rat hippocampal neurons.
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- Glia, 2001, v. 34, n. 1, p. 68, doi. 10.1002/glia.1041
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- Article
Taking Pain Out of NGF: A "Painless" NGF Mutant, Linked to Hereditary Sensory Autonomic Neuropathy Type V, with Full Neurotrophic Activity.
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- PLoS ONE, 2011, v. 6, n. 2, p. 1, doi. 10.1371/journal.pone.0017321
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Docosahexaenoic acid modulates inflammatory and antineurogenic functions of activated microglial cells.
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- Journal of Neuroscience Research, 2012, v. 90, n. 3, p. 575, doi. 10.1002/jnr.22783
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Regulation of Glial Cell Functions by PPAR-γ Natural and Synthetic Agonists.
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- PPAR Research, 2008, p. 1, doi. 10.1155/2008/864140
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- Article
PPAR-γ, Microglial Cells, and Ocular Inflammation: New Venues for Potential Therapeutic Approaches.
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- PPAR Research, 2008, p. 1, doi. 10.1155/2008/295784
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- Article
Adenosine A<sub>2A</sub> receptor stimulation restores cell functions and differentiation in Niemann-Pick type C-like oligodendrocytes.
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- Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-46268-8
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- Article
The mitochondrial uncoupling protein-2 is a master regulator of both M1 and M2 microglial responses.
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- Journal of Neurochemistry, 2015, v. 135, n. 1, p. 147, doi. 10.1111/jnc.13244
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- Article
Curcumin promotes oligodendrocyte differentiation and their protection against TNF-α through the activation of the nuclear receptor PPAR-γ.
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- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-83938-y
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- Article
Megalencephalic leukoencephalopathy with subcortical cysts protein-1 regulates epidermal growth factor receptor signaling in astrocytes.
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- Human Molecular Genetics, 2016, v. 25, n. 8, p. 1543, doi. 10.1093/hmg/ddw032
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Role of the peroxisome proliferator-activated receptor-γ (PPAR-γ) and its natural ligand 15-deoxy-Δ<sup>12,14</sup>-prostaglandin J<sub>2</sub> in the regulation of microglial functions.
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- European Journal of Neuroscience, 2000, v. 12, n. 7, p. 2215, doi. 10.1046/j.1460-9568.2000.00110.x
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- Article
HIV-gp120 affects the functional activity of oligodendrocytes and their susceptibility to complement.
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- Journal of Neuroscience Research, 1997, v. 50, n. 6, p. 946, doi. 10.1002/(SICI)1097-4547(19971215)50:6<946::AID-JNR5>3.0.CO;2-D
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Muscarinic receptor subtypes as potential targets to modulate oligodendrocyte progenitor survival, proliferation, and differentiation.
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- Developmental Neurobiology (19328451), 2012, v. 72, n. 5, p. 713, doi. 10.1002/dneu.20976
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Nuclear receptor peroxisome proliferator-activated receptor-γ is activated in rat microglial cells by the anti-inflammatory drug HCT1026, a derivative of flurbiprofen.
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- Journal of Neurochemistry, 2005, v. 92, n. 4, p. 895, doi. 10.1111/j.1471-4159.2004.02932.x
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- Article
15-Deoxy-Δ<sup>12,14</sup> -prostaglandin J<sub>2</sub> regulates the functional state and the survival of microglial cells through multiple molecular mechanisms.
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- Journal of Neurochemistry, 2003, v. 87, n. 3, p. 742, doi. 10.1046/j.1471-4159.2003.02045.x
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- Article
The Stimulation of Adenosine A<sup>2A</sup> Receptors Ameliorates the Pathological Phenotype of Fibroblasts from Niemann-Pick Type C Patients.
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- Journal of Neuroscience, 2013, v. 33, n. 39, p. 15388, doi. 10.1523/JNEUROSCI.0558-13.2013
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The nuclear receptor peroxisome proliferator-activated receptor-γ promotes oligodendrocyte differentiation through mechanisms involving mitochondria and oscillatory Ca<sup>2+</sup> waves.
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- Biological Chemistry, 2013, v. 394, n. 12, p. 1607, doi. 10.1515/hsz-2013-0152
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- Article