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- Title
Incidence and risk factors of HCV and HIV infections in a cohort of intravenous drug users in the North and East of France.
- Authors
D. LUCIDARME; A. BRUANDET; D. ILEF; J. HARBONNIER; C. JACOB; A. DECOSTER; C. DELAMARE; C. CYRAN; A.-F. VAN HOENACKER; D. FRÉMAUX; P. JOSSE; J. EMMANUELLI; Y. LE STRAT; J.-C. DESENCLOS; B. FILOCHE
- Abstract
In order to evaluate the incidence and risk factors of infection by hepatitis C virus (HCV) among injecting drug users (IDUs), we conducted a prospective cohort study of HCV- and human immunodeficiency virus (HIV)-negative IDUs in the North and East of France. A total of 231 HCV and HIV IDUs who had injected drugs at least once in their lifetime were followed up every 3 months over a 12-month period. Serum anti-HCV and anti-HIV were tested at inclusion in the study and at the end of the follow-up. Data on injecting practices were collected at inclusion and at each visit. Of the 231 participants included, 165 (71·4%) underwent a final HCV and HIV serum test. The incidence was nil for HIV infection and 9/100 person-years (95% CI 4·613·4) for HCV infection. In a multivariable analysis, we found that syringe and cotton sharing were the only independent predictive factors of HCV seroconversion.
- Subjects
HIV infections; DISEASE risk factors; HEPATITIS C; INFECTION; MULTIVARIATE analysis
- Publication
Epidemiology & Infection, 2004, Vol 132, Issue 4, p699
- ISSN
0950-2688
- Publication type
Article
- DOI
10.1017/s095026880400247x