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- Title
Clinical significance of serum urea‐to‐creatinine ratio in patients undergoing peritoneal dialysis.
- Authors
Tonomura, Shun; Uchiyama, Kiyotaka; Nakayama, Takashin; Mitsuno, Ryunosuke; Kojima, Daiki; Hama, Eriko Yoshida; Nagasaka, Tomoki; Nishimura, Erina Sugita; Kusahana, Ei; Takahashi, Rina; Yoshimoto, Norifumi; Yamaguchi, Shintaro; Morimoto, Kohkichi; Yoshida, Tadashi; Hayashi, Kaori; Kanda, Takeshi; Washida, Naoki; Itoh, Hiroshi
- Abstract
Introduction: We aimed to determine the correlation between the serum urea‐to‐creatinine ratio and residual kidney function (RKF) in patients undergoing peritoneal dialysis (PD), as well as its predictive value for PD‐related outcomes. Methods: This study included a cross‐sectional study to assess the correlation between serum urea‐to‐creatinine ratio and RKF in 50 patients on PD and a retrospective cohort study to assess the association between serum urea‐to‐creatinine ratio and PD‐related outcomes in 122 patients who initiated PD. Results: Serum urea‐to‐creatinine ratios had significant positive correlations with renal Kt/V and creatinine clearance values (r = 0.60, p < 0.001 and r = 0.61, p < 0.001, respectively). Additionally, serum urea‐to‐creatinine ratio was significantly associated with a lower risk of transfer to hemodialysis or PD/hemodialysis hybrid therapy (hazard ratio: 0.84, 95% confidence interval: 0.75–0.95). Conclusion: The serum urea‐to‐creatinine ratio can be an indicator of RKF and a prognostic factor in patients undergoing PD.
- Subjects
PERITONEAL dialysis; KIDNEY physiology; PROGNOSIS; CONFIDENCE intervals; HEMODIALYSIS; CROSS-sectional method
- Publication
Therapeutic Apheresis & Dialysis, 2023, Vol 27, Issue 6, p1103
- ISSN
1744-9979
- Publication type
Article
- DOI
10.1111/1744-9987.14030