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- Title
Analysis of Chilli Chloroplastic Photosystem II Protein D1 Interaction with the Cucumber Mosaic Virus (CMV) Coat Protein Using Computational Tools.
- Authors
POOJA, P. S.; SINDHURA, KOPPARTHI AMRUTHAVALLI; KHATIB, SHADAB M.; BHARATH, M.; KAVYA, S. S.; MUTTAPPAGOL, MANTESH; HIREMATH, SHRIDHAR S.; LAVANYA, K. P.; NINGARAJU, T. M.; REDDY, C. N. LAKSHMINARAYANA
- Abstract
Plant viruses are of significant threat to agricultural productivity worldwide, causing substantial economic losses and impacting food security. Understanding the molecular interactions between plant viruses and their hosts is essential for developing effective strategies for virus control and crop protection. In this study, we employed homology modeling and an in silico approach to investigate interactions between chilli host protein, chloroplastic photosystem II protein D1 with the coat protein of cucumber mosaic virus (CMV). CMV coat protein sequences were retrieved from genomic data bank to identify putative host targets. Subsequently, we utilized established protein-protein interaction prediction algorithms and resources to predict potential interactions between CMV proteins and host proteins. This in silico study provides a foundation for further experimental investigations, offering potential targets for the development of novel antiviral strategies and crop protection measures. From the obtained docking scores, it was presumed that CMV CP and Photosystem II protein D1 are interacting and established structural-functional relation provided a basis to propose probable hostvirus interactions in terms of virus infection and symptom development.
- Subjects
CUCUMBER mosaic virus; PHOTOSYSTEMS; PROTEIN-protein interactions; HOST plants; GENE libraries; PLANT protection
- Publication
Mysore Journal of Agricultural Sciences, 2024, Vol 58, Issue 1, p222
- ISSN
0047-8539
- Publication type
Article