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- Title
Echocardiographic Predictors of Ventricular Tachycardia.
- Authors
Catanzaro, John N.; Makaryus, John N.; Makaryus, Amgad N.; Sison, Cristina; Vavasis, Christos; Fan, Dali; Jadonath, Ram
- Abstract
Ba ckground: Patients with structural heart disease are prone to ventricular tachycardia (VT) and ventricular fibrillation (VF), which account for the majority of sudden cardiac deaths (SCDs). We sought to examine echocardiographic parameters that can predict VT as documented by implantable cardioverter-defibrillator (ICD) appropriate discharge. We examine echocardiographic parameters other than ejection fraction that may predict VT as recorded via rates of ICD discharge. Methods: Analysis of 586 patients (469 males; mean age 68 3 years; mean follow-up time of 11 14 months) was undertaken. Echo parameters assessed included left ventricular (LV) internal end diastolic/systolic dimension (LVIDd, LVIDs), relative wall thickness (RWT), and left atrial (LA) size. Results: The incidence of VT was 0.22 (114 VT episodes per 528 person-years of follow-up time). Median time-to-first VT was 3.8 years. VT was documented in 79 patients (59 first VT incidence, 20 multiple). The echocardiographic parameter associated with first VT was LVIDs .4 cm (P 0.02). Conclusion: The main echocardiographic predictor associated with the first occurrence of VT was LVIDs .4 cm. Patients with an LVIDs .4 cm were 2.5 times more likely to have an episode of VT. Changes in these echocardiographic parameters may warrant aggressive pharmacologic therapy and implantation of an ICD.
- Subjects
NEW York (State); SUDDEN death prevention; VENTRICULAR tachycardia; ACADEMIC medical centers; ALGORITHMS; CONFIDENCE intervals; ECHOCARDIOGRAPHY; IMPLANTABLE cardioverter-defibrillators; LONGITUDINAL method; MEDICAL protocols; MULTIVARIATE analysis; PROPORTIONAL hazards models; PATIENT selection; KAPLAN-Meier estimator; LOG-rank test; PREVENTION; DISEASE risk factors
- Publication
Clinical Medicine Insights: Cardiology, 2014, Issue 8, p37
- ISSN
1179-5468
- Publication type
Article
- DOI
10.4137/CMC.S18499