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- Title
No evidence for PALB2 methylation in high-grade serous ovarian cancer.
- Authors
Mikeska, Thomas; Alsop, Kathryn; Mitchell, Gillian; Bowtell, David DL; Dobrovic, Alexander
- Abstract
The article presents information on a study related to the high grade serous ovarian cancers that are a distinct histological subtype of ovarian cancer. It informs that the cancer is characterized by a dysfunctional BRCA/Fanconi anaemia (BRCA/FA) pathway, which is critical to the homologous recombination DNA repair machinery. It further informs that the methylation was investigated in 92 high-grade serous ovarian cancer samples.
- Subjects
OVARIAN cancer; HISTOLOGY; ANEMIA; DNA repair; METHYLATION
- Publication
Journal of Ovarian Research, 2013, Vol 6, Issue 1, p1
- ISSN
1757-2215
- Publication type
Article
- DOI
10.1186/1757-2215-6-26