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- Title
Highly Enantioselective Reduction of α-Methylated Nitroalkenes.
- Authors
Burda, Edyta; Reß, Tina; Winkler, Till; Giese, Carolin; Kostrov, Xenia; Huber, Tobias; Hummel, Werner; Gröger, Harald
- Abstract
Highly selective: The reduction of α‐methyl‐substituted nitroalkenes succeeds in a highly enantioselective fashion with an ene reductase from Gluconobacter oxydans. Under optimized reaction conditions the desired nitroalkanes are formed with enantiomeric excesses of up to 95% in these biotransformations.
- Subjects
ENANTIOSELECTIVE catalysis; NITROALKENES; REDUCTASES; ENZYMES; CHEMICAL synthesis
- Publication
Angewandte Chemie International Edition, 2013, Vol 52, Issue 35, p9323
- ISSN
1433-7851
- Publication type
Article
- DOI
10.1002/anie.201301814