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- Title
Isolated lung perfusion for pulmonary metastases, a review and work in progress.
- Authors
Grootenboers, Marco J. J. H.; Heeren, Jos; van Putte, Bart P.; Hendriks, Jeroen M. H.; van Boven, Wim J.; Van Schil, Paul E. Y.; Schramel, Franz M. N. H.
- Abstract
Pulmonary metastasectomy is a widely accepted treatment for many patients with pulmonary metastases from various solid tumors. Nevertheless, 5-year survival is disappointing, with rates of 25–40%, and many patients develop recurrences. Isolated lung perfusion (ILuP) is a promising new technique to deliver high-dose chemotherapy to the lungs, while minimising systemic toxicities. This procedure is technically safe and feasible; however, clinical value and efficacy remain unclear. The aim of this paper is to give a review of literature on ILuP in humans, and to describe the development of the perfusion procedure in our institute.
- Subjects
ISOLATION perfusion; LUNGS; PULMONARY circulation disorders; METASTASIS; PULMONARY gas exchange; CYSTS (Pathology); DRUG therapy
- Publication
Perfusion, 2006, Vol 21, Issue 5, p267
- ISSN
0267-6591
- Publication type
Article
- DOI
10.1177/0267659106073984