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- Title
Too lean: Time to build back true resiliency in the national blood supply.
- Authors
Barnhard, Sarah; Klapper, Ellen; Kopko, Patricia; Tran, Minh‐Ha; Ziman, Alyssa
- Abstract
Keywords: blood supply; shortage; supply chain EN blood supply shortage supply chain 2768 2771 4 09/16/21 20210901 NES 210901 INTRODUCTION Over 20 million blood donations are collected from altruistic donors, manufactured, and distributed as transfusable blood products annually in the United States.1 The processes that link blood products from the veins of donors to the veins of recipients involve complex screening and testing protocols to ensure the highest degree of safety. The hospital blood bank, recognizing blood as a critical resource, had secondary and tertiary suppliers to mitigate periodic supply chain disruptions with any one supplier. Hospital transfusion service medical directors and pathologists attempt to mitigate supply shortages by performing case-by-case triage, discussing individual blood product orders with physicians to determine whether individual transfusions can be safely delayed or deferred. In addition, clinical trials continue to expand transfusion medicine applications in the field of cellular therapies such as chimeric antigen receptor T cell (CAR-T cell), in novel gene editing for hematological disorders, and in COVID-19 convalescent plasma therapy.
- Subjects
DIRECTED blood donations; HTLV-I; HTLV; COVID-19; BLOODBORNE infections
- Publication
Transfusion, 2021, Vol 61, Issue 9, p2768
- ISSN
0041-1132
- Publication type
Article
- DOI
10.1111/trf.16614