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- Title
Natural progression of QRS duration in ICD-only patients.
- Authors
Ding, Wern Yew; Cooper, Robert; Todd, Derick; Gupta, Dhiraj; Hall, Mark; Rao, Archana; Wright, Jay; Snowdon, Richard; Waktare, Johan; Modi, Simon
- Abstract
<bold>Purpose: </bold>The aim of our study is to determine if there is a natural progression of QRSd in ICD-only patients.<bold>Methods and Results: </bold>Retrospective study over a 7-year period of 86 consecutive patients who underwent ICD-only implantation in 2008 at the Liverpool Heart and Chest Hospital, UK. The mean age at ICD implantation was 62.3 (± 11.5) years, range 24-82 years. Mean length of follow-up ECGs available was 5.0 (± 1.6) years, total of 431 patient-years. We observed a progressive prolongation of QRSd over the 7-year study period. The linear mixed model found a statistically significant (p < 0.001) increase in QRSd over time, as measured in years. Clinically important progression of QRSd to ≥ 120 ms was observed in 30% of patients after 2.7 (± 1.5) years and progression of QRSd to ≥ 150 ms was observed in 10% of patients after 2.9 (± 1.2) years.<bold>Conclusions: </bold>The natural progression of QRS duration in ICD patients may have serious implications for device implantation. Our study found that the QRS duration increased at a rate of 3.1 ms per year in ICD patients.
- Subjects
CARDIAC pacing; VENTRICULAR fibrillation; HEART failure patients; HEART failure treatment; ATRIAL fibrillation; CAUSES of death; ELECTROCARDIOGRAPHY; IMPLANTABLE cardioverter-defibrillators; LONGITUDINAL method; PROGNOSIS; SURVIVAL analysis (Biometry); RETROSPECTIVE studies; VENTRICULAR tachycardia; DISEASE progression; STROKE volume (Cardiac output); THERAPEUTICS
- Publication
Journal of Interventional Cardiac Electrophysiology, 2018, Vol 53, Issue 1, p47
- ISSN
1383-875X
- Publication type
journal article
- DOI
10.1007/s10840-018-0394-3