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Knockout of cytochrome P450 3A yields new mouse models for understanding xenobiotic metabolism.
- Published in:
- 2007
- By:
- Publication type:
- journal article
SLC1A3 contributes to L‐asparaginase resistance in solid tumors.
- Published in:
- EMBO Journal, 2019, v. 38, n. 21, p. N.PAG, doi. 10.15252/embj.2019102147
- By:
- Publication type:
- Article
ATP-binding cassette transporters limit the brain penetration of Wee1 inhibitors.
- Published in:
- Investigational New Drugs, 2018, v. 36, n. 3, p. 380, doi. 10.1007/s10637-017-0539-8
- By:
- Publication type:
- Article
P-glycoprotein and breast cancer resistance protein restrict the brain penetration of the CDK4/6 inhibitor palbociclib.
- Published in:
- Investigational New Drugs, 2015, v. 33, n. 5, p. 1012, doi. 10.1007/s10637-015-0266-y
- By:
- Publication type:
- Article
'Effect of the drug transporters ABCB1, ABCC2, and ABCG2 on the disposition and brain accumulation of the taxane analog BMS-275,183'.
- Published in:
- Investigational New Drugs, 2014, v. 32, n. 6, p. 1083, doi. 10.1007/s10637-014-0143-0
- By:
- Publication type:
- Article
Differential effects of anticoagulants on tumor development of mouse cancer cell lines B16, K1735 and CT26 in lung.
- Published in:
- Clinical & Experimental Metastasis, 2009, v. 26, n. 3, p. 171, doi. 10.1007/s10585-008-9227-6
- By:
- Publication type:
- Article
Pharmacokinetics, Brain Delivery, and Efficacy in Brain Tumor-Bearing Mice of Glutathione Pegylated Liposomal Doxorubicin (2B3-101).
- Published in:
- PLoS ONE, 2014, v. 9, n. 1, p. 1, doi. 10.1371/journal.pone.0082331
- By:
- Publication type:
- Article
EZN-2208 (PEG-SN38) Overcomes ABCG2-Mediated Topotecan Resistance in BRCA1-Deficient Mouse Mammary Tumors.
- Published in:
- PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0045248
- By:
- Publication type:
- Article
Rational combination of SHP2 and mTOR inhibition for the treatment of hepatocellular carcinoma.
- Published in:
- Molecular Oncology, 2023, v. 17, n. 6, p. 964, doi. 10.1002/1878-0261.13377
- By:
- Publication type:
- Article
Effect of the drug transporters ABCG2, Abcg2, ABCB1 and ABCC2 on the disposition, brain accumulation and myelotoxicity of the aurora kinase B inhibitor barasertib and its more active form barasertib-hydroxy-QPA.
- Published in:
- Investigational New Drugs, 2013, v. 31, n. 5, p. 1125, doi. 10.1007/s10637-013-9923-1
- By:
- Publication type:
- Article
Erratum to: Effect of the drug transporters ABCG2, Abcg2, ABCB1 and ABCC2 on the disposition, brain accumulation and myelotoxicity of the aurora kinase B inhibitor barasertib and its more active form barasertib-hydroxy-QPA.
- Published in:
- 2013
- By:
- Publication type:
- Correction Notice
Restricted brain penetration of the tyrosine kinase inhibitor erlotinib due to the drug transporters P-gp and BCRP.
- Published in:
- Investigational New Drugs, 2012, v. 30, n. 2, p. 443, doi. 10.1007/s10637-010-9569-1
- By:
- Publication type:
- Article
The effect of P-gp (Mdr1a/1b), BCRP (Bcrp1) and P-gp/BCRP inhibitors on the in vivo absorption, distribution, metabolism and excretion of imatinib.
- Published in:
- Investigational New Drugs, 2009, v. 27, n. 1, p. 31, doi. 10.1007/s10637-008-9138-z
- By:
- Publication type:
- Article
Comments on: "Synergistic activity of mTORC1/2 kinase and MEK inhibitors suppresses pediatric low-grade glioma tumorigenicity and vascularity".
- Published in:
- Neuro-Oncology, 2020, v. 22, n. 9, p. 1404, doi. 10.1093/neuonc/noaa112
- By:
- Publication type:
- Article
MEK/MELK inhibition and blood–brain barrier deficiencies in atypical teratoid/rhabdoid tumors.
- Published in:
- Neuro-Oncology, 2020, v. 22, n. 1, p. 58, doi. 10.1093/neuonc/noz151
- By:
- Publication type:
- Article
Selective inhibition of HDAC class IIA as therapeutic intervention for KMT2A-rearranged acute lymphoblastic leukemia.
- Published in:
- Communications Biology, 2024, p. 1, doi. 10.1038/s42003-024-06916-w
- By:
- Publication type:
- Article
Magnetic resonance imaging-based detection of glial brain tumors in mice after antiangiogenic treatment.
- Published in:
- International Journal of Cancer, 2008, v. 122, n. 9, p. 1981, doi. 10.1002/ijc.23306
- By:
- Publication type:
- Article
MRP2 (ABCC2) transports taxanes and confers paclitaxel resistance and both processes are stimulated by probenecid.
- Published in:
- International Journal of Cancer, 2005, v. 116, n. 5, p. 824, doi. 10.1002/ijc.21013
- By:
- Publication type:
- Article
Drug-induced histone eviction from open chromatin contributes to the chemotherapeutic effects of doxorubicin.
- Published in:
- Nature Communications, 2013, v. 4, n. 5, p. 1908, doi. 10.1038/ncomms2921
- By:
- Publication type:
- Article
Mps1 inhibitors synergise with low doses of taxanes in promoting tumour cell death by enhancement of errors in cell division.
- Published in:
- 2018
- By:
- Publication type:
- journal article
Molecular Imaging of ABCB1 and ABCG2 Inhibition at the Human Blood-Brain Barrier Using Elacridar and <sup>11</sup>C-Erlotinib PET.
- Published in:
- Journal of Nuclear Medicine, 2018, v. 59, n. 6, p. 973, doi. 10.2967/jnumed.117.195800
- By:
- Publication type:
- Article
Diversifying the anthracycline class of anti-cancer drugs identifies aclarubicin for superior survival of acute myeloid leukemia patients.
- Published in:
- Molecular Cancer, 2024, v. 23, n. 1, p. 1, doi. 10.1186/s12943-024-02034-7
- By:
- Publication type:
- Article
Determination of topotecan in human and mouse plasma and in mouse tissue homogenates by reversed-phase high-performance liquid chromatography.
- Published in:
- Biomedical Chromatography, 2007, v. 21, n. 11, p. 1191, doi. 10.1002/bmc.874
- By:
- Publication type:
- Article
Determination of imatinib mesylate and its main metabolite (CGP74588) in human plasma and murine specimens by ion-pairing reversed-phase high-performance liquid chromatography.
- Published in:
- Biomedical Chromatography, 2007, v. 21, n. 7, p. 747, doi. 10.1002/bmc.816
- By:
- Publication type:
- Article
The effect of P-glycoprotein and cytochrome P450 3a on the oral bioavailability of vinorelbine in mice.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2006, v. 57, n. 6, p. 819, doi. 10.1007/s00280-005-0088-2
- By:
- Publication type:
- Article
Metabolism of docetaxel in mice.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2005, v. 56, n. 3, p. 299, doi. 10.1007/s00280-004-0945-4
- By:
- Publication type:
- Article
The influence of the P-glycoprotein inhibitor zosuquidar trihydrochloride (LY335979) on the brain penetration of paclitaxel in mice.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2004, v. 53, n. 2, p. 173, doi. 10.1007/s00280-003-0720-y
- By:
- Publication type:
- Article
Entrapment by Cremophor EL decreases the absorption of paclitaxel from the gut.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2002, v. 49, n. 2, p. 119, doi. 10.1007/s00280-001-0394-2
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- Publication type:
- Article
A phase I and pharmacokinetic study of bi-daily dosing of oral paclitaxel in combination with cyclosporin A.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2001, v. 47, n. 4, p. 347, doi. 10.1007/s002800000226
- By:
- Publication type:
- Article
The impact of P-glycoprotein and breast cancer resistance protein on the brain pharmacokinetics and pharmacodynamics of a panel of MEK inhibitors.
- Published in:
- International Journal of Cancer, 2018, v. 142, n. 2, p. 381, doi. 10.1002/ijc.31052
- By:
- Publication type:
- Article
ABCB1 and ABCG2 restrict the brain penetration of a panel of novel EZH2-Inhibitors.
- Published in:
- International Journal of Cancer, 2015, v. 137, n. 8, p. 2007, doi. 10.1002/ijc.29566
- By:
- Publication type:
- Article
In vivo disposition of doxorubicin is affected by mouse Oatp1a/1b and human OATP1A/1B transporters.
- Published in:
- International Journal of Cancer, 2014, v. 135, n. 7, p. 1700, doi. 10.1002/ijc.28797
- By:
- Publication type:
- Article
Dual mTORC1 and mTORC2 inhibitor Palomid 529 penetrates the Blood-Brain Barrier without restriction by ABCB1 and ABCG2.
- Published in:
- International Journal of Cancer, 2013, v. 133, n. 5, p. 1222, doi. 10.1002/ijc.28126
- By:
- Publication type:
- Article
Tumor microvasculature supports proliferation and expansion of glioma-propagating cells.
- Published in:
- International Journal of Cancer, 2009, v. 125, n. 5, p. 1222, doi. 10.1002/ijc.24408
- By:
- Publication type:
- Article
ATP-binding cassette transporter inhibitor potency and substrate drug affinity are critical determinants of successful drug delivery enhancement to the brain.
- Published in:
- Fluids & Barriers of the CNS, 2024, v. 21, n. 1, p. 1, doi. 10.1186/s12987-024-00562-4
- By:
- Publication type:
- Article
Indisulam synergizes with palbociclib to induce senescence through inhibition of CDK2 kinase activity.
- Published in:
- PLoS ONE, 2022, v. 17, n. 9, p. 1, doi. 10.1371/journal.pone.0273182
- By:
- Publication type:
- Article
Acquired and intrinsic resistance to vemurafenib in BRAF<sup>V600E</sup>‐driven melanoma brain metastases.
- Published in:
- FEBS Open Bio, 2024, v. 14, n. 1, p. 96, doi. 10.1002/2211-5463.13730
- By:
- Publication type:
- Article
The G2 checkpoint-a node-based molecular switch.
- Published in:
- FEBS Open Bio, 2017, v. 7, n. 4, p. 439, doi. 10.1002/2211-5463.12206
- By:
- Publication type:
- Article
Tooth Formation as Experimental Model to Study Chemotherapy on Tissue Development: Effect of a Specific Dose of Temozolomide/Veliparib.
- Published in:
- Genes, 2022, v. 13, n. 7, p. 1198, doi. 10.3390/genes13071198
- By:
- Publication type:
- Article
Non-therapeutic plasma levels in individuals utilizing curcumin supplements in daily life.
- Published in:
- Frontiers in Nutrition, 2023, p. 1, doi. 10.3389/fnut.2023.1267035
- By:
- Publication type:
- Article
Effects of the selective MPS1 inhibitor MPS1-IN-3 on glioblastoma sensitivity to antimitotic drugs.
- Published in:
- 2013
- By:
- Publication type:
- journal article
Effects of the Selective MPSI Inhibitor MPSI-IN-3 on Glioblastoma Sensitivity to Antimitotic Drugs.
- Published in:
- JNCI: Journal of the National Cancer Institute, 2013, v. 105, n. 17, p. 1322, doi. 10.1093/jnci/djt168
- By:
- Publication type:
- Article
Multiple low dose therapy as an effective strategy to treat EGFR inhibitor-resistant NSCLC tumours.
- Published in:
- Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-16952-9
- By:
- Publication type:
- Article
Concerns about anti-angiogenic treatment in patients with glioblastoma multiforme.
- Published in:
- 2009
- By:
- Publication type:
- journal article