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- Title
Secondary Metabolites from the Endophytic Fungus Xylaria grammica and Their Anti-Inflammatory Activities.
- Authors
Lv, Liu-Xia; Mo, Tu-Xiang; Liang, Min; Huang, Li-Li; Li, Ben-Chao; Qin, Xiao-Ya; Huang, Xi-Shan; Li, Jun; Xu, Wei-Feng; Yang, Rui-Yun
- Abstract
Herein, we report on the isolation and anti-inflammatory activities of these compounds. Compound B 6 b showed significant anti-inflammatory activity by inhibiting the production of NO in LPS-induced RAW 264.7 cells with IC SB 50 sb value of 23.24 ± 1.3 M (indomethacin IC SB 50 sb 33.50 ± 1.13 M), the other compounds showed no obvious anti-inflammatory activity ( B 1-5 b , IC SB 50 sb > 50 M). Among them, compound B 4 b was isolated from genus I Xylaria i firstly I , i and the other compounds were isolated from I Xylaria grammica i for the first time. Graph All compounds were tested for their anti-inflammatory activities [[4], [20]].
- Subjects
ENDOPHYTIC fungi; ANTI-inflammatory agents; METABOLITES; XYLARIA; PLANT metabolites; ETHYL acetate
- Publication
Chemistry of Natural Compounds, 2023, Vol 59, Issue 1, p154
- ISSN
0009-3130
- Publication type
Article
- DOI
10.1007/s10600-023-03940-w