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- Title
Topical tacrolimus therapy in the management of lower extremity ulcers due to prolidase deficiency.
- Authors
Good, Allison J.; Nielson, Colton B.; Schoch, Jennifer J.
- Abstract
Prolidase deficiency is a rare autosomal recessive disorder characterized by cutaneous ulcers, facial dysmorphism, recurrent infections, and intellectual disability. We report a unique case of a 6‐year‐old boy with prolidase deficiency and Crohn's disease who presented with lower extremity ulcers. Cutaneous ulcers due to prolidase deficiency are historically resistant to treatment, and we report success with the novel use of topical tacrolimus.
- Subjects
LEG; CROHN'S disease; ULCERS; FACIAL abnormalities
- Publication
Pediatric Dermatology, 2019, Vol 36, Issue 6, p926
- ISSN
0736-8046
- Publication type
Article
- DOI
10.1111/pde.13973