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- Title
Searching for predictors of atherosclerotic bilateral renal artery stenosis.
- Authors
Geavlete, Dana-Oliviana; Beladan, Carmen; Călin, Andreea; Croitoru, Marian; Jurcuţ, Ruxandra; Tăutu, Oana; Popescu, Bogdan A.; Ginghină, Carmen
- Abstract
Objectives - Bilateral atherosclerotic renal artery stenosis (RAS) implies a worse prognosis when compared to unilateral RAS concerning overall mortality and kidney function. The study aimed to compare the extension of atherosclerotic (ATS) disease in consecutive patients wiThsignificant uni- versus bilateral RAS. Methods - 58 patients referred to renal angiography for suspected RAS were prospectively enrolled and diagnosed wiThsignificant (>60%) unilateral (n=31) and bilateral (n=28) stenosis. The evaluation protocol included cardiac history, known duration of hypertension, cardio-vascular risk factors, features of extracoronary vascular disease, related comorbidities and renal function. In all patients, coronary artery disease (CAD) was confirmed by cardiac catheterization while significant carotid artery disease (CAS) was assessed by carotidian angiography. Results - The renal function recorded in patients from the bilateral RAS group was significantly lower when compared to the unilateral series, regardless of the used parameter (serum creatinine levels and estimated glomerular filtration rate - eGRF). Moreover, the prevalence of significant CAS was higher in the bilateral RAS group. Conclusions - By combining the presence of bilateral significant CAS wiThthe eGFR reduction, there was determined an increase in the probability of correctly predicting the presence of bilateral RAS from 73.1% (bilateral CAS alone) and 76.9% (eGFR alone) to 78.8%.
- Subjects
ARTERIAL stenosis diagnosis; ARTERIAL stenosis treatment; ATHEROSCLEROSIS; KIDNEY diseases; HYPERTENSION; PATIENTS
- Publication
Romanian Journal of Cardiology, 2015, Vol 25, Issue 1, p1
- ISSN
1220-658X
- Publication type
Article