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- Title
The evolution of electrocardiographic changes in ST segment elevation myocardial infarction during the optimal therapeutic decision interval.
- Authors
Mirescu, Magda Ruxandra; Nicolae, Camelia; Gheorghe, Gabriela; Ciobanu, Ana; Hodorogea, Andreea; Almarichi, Simona; Onceanu, Sorina; Ginghina, Carmen; intoiu, Ion Ț; Nanea, Ioan Tiberiu
- Abstract
Objectives - Electrocardiogram (ECG) remains a landmark concerning ST segment elevation myocardial infarction (STEMI) diagnostic and prognostic, offering data for optimizing treatment strategy. The trial quantified ischemic lesions (ST segment) and loss of myocardial mass (R wave) during the optimal therapeutic decision interval. Methods -ST segment elevation magnitude and R wave amplitude correlated with pain onset-presentation interval were measured for 100 STEMI patients with TIMI 0/1 flow. Results - The ST magnitude during the 0-30 minutes' interval displayed substantial variability (increasing 46.16%, stationary 30.87%, decreasing 22.96%). The R wave amplitude emphasized a mostly decreasing tendency (74.82% of cases) or remained stationary (25.18%). During the optimal therapeutic decision interval, a statistically significant correlation was established between the ST segment elevation magnitude (increasing, stationary or decreasing) and the decreasing R wave amplitude (r=0.45, p<0.0001; r=0.29, p<0.001; r=0.22, p<0.001). Conclusions - R wave amplitude analysis might be included in the electric description of STEMI, preserving a relation not only with the ST segment elevation rise but also with its' decrease or constant levels. An eventual correlation between the R wave reduction and the ST segment elevation could suggest a necrosis' evolution and may represent an additional useful parameter while setting the indication for reperfusion treatment.
- Subjects
ELECTROCARDIOGRAPHY; MYOCARDIAL infarction diagnosis; MYOCARDIAL infarction; NECROSIS; RAYLEIGH waves; PROGNOSIS
- Publication
Romanian Journal of Cardiology, 2014, Vol 24, Issue 3, p163
- ISSN
1220-658X
- Publication type
Article