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Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-29688-5
By:
- de Vries, Laura E.;
- Jansen, Patrick A. M.;
- Barcelo, Catalina;
- Munro, Justin;
- Verhoef, Julie M. J.;
- Pasaje, Charisse Flerida A.;
- Rubiano, Kelly;
- Striepen, Josefine;
- Abla, Nada;
- Berning, Luuk;
- Bolscher, Judith M.;
- Demarta-Gatsi, Claudia;
- Henderson, Rob W. M.;
- Huijs, Tonnie;
- Koolen, Karin M. J.;
- Tumwebaze, Patrick K.;
- Yeo, Tomas;
- Aguiar, Anna C. C.;
- Angulo-Barturen, Iñigo;
- Churchyard, Alisje
Publication type:
Article
Assessment of the transmission blocking activity of antimalarial compounds by membrane feeding assays using natural Plasmodium falciparum gametocyte isolates from West-Africa.
Published in:
PLoS ONE, 2023, v. 18, n. 9, p. 1, doi. 10.1371/journal.pone.0284751
By:
- B. Henry, Noëlie;
- Soulama, Issiaka;
- S. Sermé, Samuel;
- Bolscher, Judith M.;
- T. G. Huijs, Tonnie;
- S. Coulibaly, Aboubacar;
- Sombié, Salif;
- Ouédraogo, Nicolas;
- Diarra, Amidou;
- Zongo, Soumanaba;
- Guelbéogo, Wamdaogo M.;
- Nébié, Issa;
- Sirima, Sodiomon B.;
- Tiono, Alfred B.;
- Pietro, Alano;
- Collins, Katharine A.;
- Dechering, Koen J.;
- Bousema, Teun
Publication type:
Article
Multifaceted effects of synthetic TLR2 ligand and Legionella pneumophilia on Treg-mediated suppression of T cell activation.
Published in:
BMC Immunology, 2011, v. 12, n. 1, p. 23, doi. 10.1186/1471-2172-12-23
By:
- van Maren, Wendy W. C.;
- Nierkens, Stefan;
- Toonen, Liza W.;
- Bolscher, Judith M.;
- Sutmuller, Roger P. M.;
- Adema, Gosse J.
Publication type:
Article
Analysis of a Multi-component Multi-stage Malaria Vaccine Candidate—Tackling the Cocktail Challenge.
Published in:
PLoS ONE, 2015, v. 10, n. 7, p. 1, doi. 10.1371/journal.pone.0131456
By:
- Boes, Alexander;
- Spiegel, Holger;
- Voepel, Nadja;
- Edgue, Gueven;
- Beiss, Veronique;
- Kapelski, Stephanie;
- Fendel, Rolf;
- Scheuermayer, Matthias;
- Pradel, Gabriele;
- Bolscher, Judith M.;
- Behet, Marije C.;
- Dechering, Koen J.;
- Hermsen, Cornelus C.;
- Sauerwein, Robert W.;
- Schillberg, Stefan;
- Reimann, Andreas;
- Fischer, Rainer
Publication type:
Article
Antimalarial pantothenamide metabolites target acetyl–coenzyme A biosynthesis in Plasmodium falciparum.
Published in:
Science Translational Medicine, 2019, v. 11, n. 510, p. 1, doi. 10.1126/scitranslmed.aas9917
By:
- Schalkwijk, Joost;
- Allman, Erik L.;
- Jansen, Patrick A. M.;
- de Vries, Laura E.;
- Verhoef, Julie M. J.;
- Jackowski, Suzanne;
- Botman, Peter N. M.;
- Beuckens-Schortinghuis, Christien A.;
- Koolen, Karin M. J.;
- Bolscher, Judith M.;
- Vos, Martijn W.;
- Miller, Karen;
- Reeves, Stacy A.;
- Pett, Helmi;
- Trevitt, Graham;
- Wittlin, Sergio;
- Scheurer, Christian;
- Sax, Sibylle;
- Fischli, Christoph;
- Angulo-Barturen, Iñigo
Publication type:
Article
Analysis of the dose-dependent stage-specific in vitro efficacy of a multi-stage malaria vaccine candidate cocktail.
Published in:
Malaria Journal, 2016, v. 15, p. 1, doi. 10.1186/s12936-016-1328-0
By:
- Boes, Alexander;
- Spiegel, Holger;
- Kastilan, Robin;
- Bethke, Susanne;
- Voepel, Nadja;
- Chudobová, Ivana;
- Bolscher, Judith M.;
- Dechering, Koen J.;
- Fendel, Rolf;
- Buyel, Johannes F.;
- Reimann, Andreas;
- Schillberg, Stefan;
- Fischer, Rainer
Publication type:
Article
A novel multiple-stage antimalarial agent that inhibits protein synthesis.
Published in:
Nature, 2015, v. 522, n. 7556, p. 315, doi. 10.1038/nature14451
By:
- Baragaña, Beatriz;
- Hallyburton, Irene;
- Lee, Marcus C. S.;
- Norcross, Neil R.;
- Grimaldi, Raffaella;
- Otto, Thomas D.;
- Proto, William R.;
- Blagborough, Andrew M.;
- Meister, Stephan;
- Wirjanata, Grennady;
- Ruecker, Andrea;
- Upton, Leanna M.;
- Abraham, Tara S.;
- Almeida, Mariana J.;
- Pradhan, Anupam;
- Porzelle, Achim;
- Martínez, María Santos;
- Bolscher, Judith M.;
- Woodland, Andrew;
- Norval, Suzanne
Publication type:
Article
A P. falciparum NF54 Reporter Line Expressing mCherry-Luciferase in Gametocytes, Sporozoites, and Liver-Stages.
Published in:
Frontiers in Cellular & Infection Microbiology, 2019, v. 9, p. N.PAG, doi. 10.3389/fcimb.2019.00096
By:
- Marin-Mogollon, Catherin;
- Salman, Ahmed M.;
- Koolen, Karin M. J.;
- Bolscher, Judith M.;
- van Pul, Fiona J. A.;
- Miyazaki, Shinya;
- Imai, Takashi;
- Othman, Ahmad Syibli;
- Ramesar, Jai;
- van Gemert, Geert-Jan;
- Kroeze, Hans;
- Chevalley-Maurel, Severine;
- Franke-Fayard, Blandine;
- Sauerwein, Robert W.;
- Hill, Adrian V. S.;
- Dechering, Koen J.;
- Janse, Chris J.;
- Khan, Shahid M.
Publication type:
Article
Assessment of the drugability of initial malaria infection through miniaturized sporozoite assays and high-throughput screening.
Published in:
Communications Biology, 2023, v. 6, n. 1, p. 1, doi. 10.1038/s42003-023-04599-3
By:
- Miglianico, Marie;
- Bolscher, Judith M.;
- Vos, Martijn W.;
- Koolen, Karin J. M.;
- de Bruijni, Marloes;
- Rajagopal, Deeya S.;
- Chen, Emily;
- Kiczun, Michael;
- Gray, David;
- Campo, Brice;
- Sauerwein, Robert W.;
- Dechering, Koen J.
Publication type:
Article

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