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Phosphoproteomic profiling of T cell acute lymphoblastic leukemia reveals targetable kinases and combination treatment strategies.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-28682-1
By:
- Cordo', Valentina;
- Meijer, Mariska T.;
- Hagelaar, Rico;
- de Goeij-de Haas, Richard R.;
- Poort, Vera M.;
- Henneman, Alex A.;
- Piersma, Sander R.;
- Pham, Thang V.;
- Oshima, Koichi;
- Ferrando, Adolfo A.;
- Zaman, Guido J. R.;
- Jimenez, Connie R.;
- Meijerink, Jules P. P.
Publication type:
Article
MAFB enhances oncogenic Notch signaling in T cell acute lymphoblastic leukemia.
Published in:
Science Signaling, 2017, v. 10, n. 505, p. 1, doi. 10.1126/scisignal.aam6846
By:
- Pajcini, Kostandin V.;
- Lanwei Xu;
- Lijian Shao;
- Petrovic, Jelena;
- Palasiewicz, Karol;
- Yumi Ohtani;
- Bailis, Will;
- Lee, Curtis;
- Wertheim, Gerald B.;
- Mani, Rajeswaran;
- Musuthamy, Natarajan;
- Yunlei Li;
- Meijerink, Jules P. P.;
- Blacklow, Stephen C.;
- Faryabi, Robert B.;
- Cherry, Sara;
- Pear, Warren S.
Publication type:
Article
Lentiviral gene transfer into human and murine hematopoietic stem cells: size matters.
Published in:
BMC Research Notes, 2016, v. 9, p. 1, doi. 10.1186/s13104-016-2118-z
By:
- Canté-Barrett, Kirsten;
- Mendes, Rui D.;
- Smits, Willem K.;
- van Helsdingen-van Wijk, Yvette M.;
- Pieters, Rob;
- Meijerink, Jules P. P.
Publication type:
Article
Reverse engineering of TLX oncogenic transcriptional networks identifies RUNX1 as tumor suppressor in T-ALL.
Published in:
Nature Medicine, 2012, v. 18, n. 3, p. 436, doi. 10.1038/nm.2610
By:
- Della Gatta, Giusy;
- Palomero, Teresa;
- Perez-Garcia, Arianne;
- Ambesi-Impiombato, Alberto;
- Bansal, Mukesh;
- Carpenter, Zachary W;
- De Keersmaecker, Kim;
- Sole, Xavier;
- Xu, Luyao;
- Paietta, Elisabeth;
- Racevskis, Janis;
- Wiernik, Peter H;
- Rowe, Jacob M;
- Meijerink, Jules P;
- Califano, Andrea;
- Ferrando, Adolfo A
Publication type:
Article
Oncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia.
Published in:
Nature Genetics, 2011, v. 43, n. 10, p. 932, doi. 10.1038/ng.924
By:
- Zenatti, Priscila P;
- Ribeiro, Daniel;
- Li, Wenqing;
- Zuurbier, Linda;
- Silva, Milene C;
- Paganin, Maddalena;
- Tritapoe, Julia;
- Hixon, Julie A;
- Silveira, André B;
- Cardoso, Bruno A;
- Sarmento, Leonor M;
- Correia, Nádia;
- Toribio, Maria L;
- Kobarg, Jörg;
- Horstmann, Martin;
- Pieters, Rob;
- Brandalise, Silvia R;
- Ferrando, Adolfo A;
- Meijerink, Jules P;
- Durum, Scott K
Publication type:
Article
Deletion of the protein tyrosine phosphatase gene PTPN2 in T-cell acute lymphoblastic leukemia.
Published in:
Nature Genetics, 2010, v. 42, n. 6, p. 530, doi. 10.1038/ng.587
By:
- Kleppe, Maria;
- Lahortiga, Idoya;
- El Chaar, Tiama;
- De Keersmaecker, Kim;
- Mentens, Nicole;
- Graux, Carlos;
- Van Roosbroeck, Katrien;
- Ferrando, Adolfo A;
- Langerak, Anton W;
- Meijerink, Jules P P;
- Sigaux, François;
- Haferlach, Torsten;
- Wlodarska, Iwona;
- Vandenberghe, Peter;
- Soulier, Jean;
- Cools, Jan
Publication type:
Article
Duplication of the MYB oncogene in T cell acute lymphoblastic leukemia.
Published in:
Nature Genetics, 2007, v. 39, n. 5, p. 593, doi. 10.1038/ng2025
By:
- Lahortiga, Idoya;
- De Keersmaecker, Kim;
- Van Vlierberghe, Pieter;
- Graux, Carlos;
- Cauwelier, Barbara;
- Lambert, Frederic;
- Mentens, Nicole;
- Beverloo, H. Berna;
- Pieters, Rob;
- Speleman, Frank;
- Odero, Maria D.;
- Bauters, Marijke;
- Froyen, Guy;
- Marynen, Peter;
- Vandenberghe, Peter;
- Wlodarska, Iwona;
- Meijerink, Jules P. P.;
- Cools, Jan
Publication type:
Article
High-resolution identification of balanced and complex chromosomal rearrangements by 4C technology.
Published in:
Nature Methods, 2009, v. 6, n. 11, p. 837, doi. 10.1038/nmeth.1391
By:
- Simonis, Marieke;
- Klous, Petra;
- Homminga, Irene;
- Galjaard, Robert-Jan;
- Rijkers, Erik-Jan;
- Grosveld, Frank;
- Meijerink, Jules P. P.;
- de Laat, Wouter
Publication type:
Article
Angiopoietin-Like Protein 3 Promotes Preservation of Stemness during <i>Ex Vivo</i> Expansion of Murine Hematopoietic Stem Cells.
Published in:
PLoS ONE, 2014, v. 9, n. 8, p. 1, doi. 10.1371/journal.pone.0105642
By:
- Farahbakhshian, Elnaz;
- Verstegen, Monique M.;
- Visser, Trudi P.;
- Kheradmandkia, Sima;
- Geerts, Dirk;
- Arshad, Shazia;
- Riaz, Noveen;
- Grosveld, Frank;
- van Til, Niek P.;
- Meijerink, Jules P. P.
Publication type:
Article
Pediatric Precursor B-Cell Lymphoblastic Malignancies: From Extramedullary to Medullary Involvement.
Published in:
Cancers, 2022, v. 14, n. 16, p. 3895, doi. 10.3390/cancers14163895
By:
- Kroeze, Emma;
- Arias Padilla, Laura;
- Bakker, Max;
- Boer, Judith M.;
- Hagleitner, Melanie M.;
- Burkhardt, Birgit;
- Mori, Takeshi;
- Attarbaschi, Andishe;
- Verdú-Amorós, Jaime;
- Pillon, Marta;
- Anderzhanova, Liliya;
- Kabíčková, Edita;
- Chiang, Alan K. S.;
- Kebudi, Rejin;
- Mellgren, Karin;
- Lazic, Jelena;
- Jazbec, Janez;
- Meijerink, Jules P. P.;
- Beishuizen, Auke;
- Loeffen, Jan L. C.
Publication type:
Article
A Molecular Test for Quantifying Functional Notch Signaling Pathway Activity in Human Cancer.
Published in:
Cancers, 2020, v. 12, n. 11, p. 3142, doi. 10.3390/cancers12113142
By:
- Canté-Barrett, Kirsten;
- Holtzer, Laurent;
- van Ooijen, Henk;
- Hagelaar, Rico;
- Cordo', Valentina;
- Verhaegh, Wim;
- van de Stolpe, Anja;
- Meijerink, Jules P. P.
Publication type:
Article
Loss of CD44<sup>dim</sup> Expression from Early Progenitor Cells Marks T-Cell Lineage Commitment in the Human Thymus.
Published in:
Frontiers in Immunology, 2017, v. 7/8, p. 1, doi. 10.3389/fimmu.2017.00032
By:
- Canté-Barrett, Kirsten;
- Mendes, Rui D.;
- Yunlei Li;
- Vroegindeweij, Eric;
- Pike-Overzet, Karin;
- Wabeke, Tamara;
- Langerak, Anton W.;
- Pieters, Rob;
- Staal, Frank J. T.;
- Meijerink, Jules P. P.
Publication type:
Article
Trib2 Suppresses Tumor Initiation in Notch-Driven T-ALL.
Published in:
PLoS ONE, 2016, v. 11, n. 5, p. 1, doi. 10.1371/journal.pone.0155408
By:
- Stein, Sarah J.;
- Mack, Ethan A.;
- Rome, Kelly S.;
- Pajcini, Kostandin V.;
- Ohtani, Takuya;
- Xu, Lanwei;
- Li, Yunlei;
- Meijerink, Jules P. P.;
- Faryabi, Robert B.;
- Pear, Warren S.
Publication type:
Article
The Nuclear Effector of Wnt-Signaling, Tcf1, Functions as a T-Cell–Specific Tumor Suppressor for Development of Lymphomas
Published in:
PLoS Biology, 2012, v. 10, n. 11, p. 1, doi. 10.1371/journal.pbio.1001430
By:
- Tiemessen, Machteld M.;
- Baert, Miranda R. M.;
- Schonewille, Tom;
- Brugman, Martijn H.;
- Famili, Farbod;
- Salvatori, Daniela C. F.;
- Meijerink, Jules P. P.;
- Ozbek, Ugur;
- Clevers, Hans;
- van Dongen, Jacques J. M.;
- Staal, Frank J. T.
Publication type:
Article
High incidence of t(7;12)(q36;p13) in infant AML but not in infant ALL, with a dismal outcome and ectopic expression of HLXB9.
Published in:
Genes, Chromosomes & Cancer, 2006, v. 45, n. 8, p. 731, doi. 10.1002/gcc.20335
By:
- Anne R. M. von Bergh;
- Ellen van Drunen;
- Elisabeth R. van Wering;
- Laura J. C. M. van Zutven;
- Ina Hainmann;
- Gudmar Lönnerholm;
- Jules P. Meijerink;
- Rob Pieters;
- H. Berna Beverloo
Publication type:
Article
High frequency of copy number alterations in myeloid leukaemia of Down syndrome.
Published in:
British Journal of Haematology, 2012, v. 158, n. 6, p. 800, doi. 10.1111/j.1365-2141.2012.09224.x
By:
- Blink, Marjolein;
- Heuvel-Eibrink, Marry M.;
- Aalbers, Anna M.;
- Balgobind, Brian V.;
- Hollink, Iris H. I. M.;
- Meijerink, Jules P. P.;
- Velden, Vincent H. J.;
- Beverloo, Berna H.;
- Haas, Valerie;
- Hasle, Henrik;
- Reinhardt, Dirk;
- Klusmann, Jan-Henning;
- Pieters, Rob;
- Calado, Rodrigo T.;
- Zwaan, Christian M.
Publication type:
Article
Correct interpretation of T-ALL oncogene expression relies on normal human thymocyte subsets as reference material.
Published in:
British Journal of Haematology, 2012, v. 157, n. 1, p. 142, doi. 10.1111/j.1365-2141.2011.08926.x
By:
- Larmonie, Nicole S. D.;
- Dik, Willem A.;
- van der Velden, Vincent H. J.;
- Hoogeveen, Patricia G.;
- Beverloo, H. Berna;
- Meijerink, Jules P. P.;
- van Dongen, Jacques J. M.;
- Langerak, Anton W.
Publication type:
Article
Molecular-genetic insights in paediatric T-cell acute lymphoblastic leukaemia.
Published in:
British Journal of Haematology, 2008, v. 143, n. 2, p. 153, doi. 10.1111/j.1365-2141.2008.07314.x
By:
- Van Vlierberghe, Pieter;
- Pieters, Rob;
- Beverloo, H. Berna;
- Meijerink, Jules P. P.
Publication type:
Article
IL-7 Receptor Mutations and Steroid Resistance in Pediatric T cell Acute Lymphoblastic Leukemia: A Genome Sequencing Study.
Published in:
2016
By:
- Li, Yunlei;
- Buijs-Gladdines, Jessica G. C. A. M.;
- Canté-Barrett, Kirsten;
- Stubbs, Andrew P.;
- Vroegindeweij, Eric M.;
- Smits, Willem K.;
- van Marion, Ronald;
- Dinjens, Winand N. M.;
- Horstmann, Martin;
- Kuiper, Roland P.;
- Buijsman, Rogier C.;
- Zaman, Guido J. R.;
- van der Spek, Peter J.;
- Pieters, Rob;
- Meijerink, Jules P. P.
Publication type:
journal article
Reversal of IKZF1-induced glucocorticoid resistance by dual targeting of AKT and ERK signaling pathways.
Published in:
Frontiers in Oncology, 2022, v. 12, p. 1, doi. 10.3389/fonc.2022.905665
By:
- Butler, Miriam;
- Vervoort, Britt M. T.;
- van Ingen Schenau, Dorette S.;
- Jongeneel, Lieneke;
- van der Zwet, Jordy C. G.;
- Marke, René;
- Meijerink, Jules P. P.;
- Scheijen, Blanca;
- van der Meer, Laurens T.;
- van Leeuwen, Frank N.
Publication type:
Article

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