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- Title
ACCF/ACG/AHA 2010 Expert Consensus Document on the Concomitant Use of Proton Pump Inhibitors and Thienopyridines: A Focused Update of the ACCF/ACG/AHA 2008 Expert Consensus Document on Reducing the Gastrointestinal Risks of Antiplatelet Therapy and NSAID Use
- Authors
Abraham, Neena S; Hlatky, Mark A; Antman, Elliott M; Bhatt, Deepak L; Bjorkman, David J; Clark, Craig B; Furberg, Curt D; Johnson, David A; Kahi, Charles J; Laine, Loren; Mahaffey, Kenneth W; Quigley, Eamonn M; Scheiman, James; Sperling, Laurence S; Tomaselli, Gordon F
- Abstract
The article discusses the use of proton pump inhibitors (PPI) and thienopyridines as an alternative treatment for cardiovascular (CV) diseases. It says that clopidogrel is more effective than aspirin in reducing main CV events. It mentions the greater risk for gastrointestinal (GI) bleeding in using clopidogrel and aspirin. It adds that the use of PPI lessens the risk of upper GI bleeding compared with no therapy. It suggests the regular use of PPI to reduce the platelet impacts of clopidogrel.
- Subjects
ALTERNATIVE treatment for cardiovascular diseases; CLOPIDOGREL; PROTON pump inhibitors; GASTROINTESTINAL hemorrhage; ASPIRIN; PREVENTION
- Publication
American Journal of Gastroenterology (Springer Nature), 2010, Vol 105, Issue 12, p2533
- ISSN
0002-9270
- Publication type
Article
- DOI
10.1038/ajg.2010.445