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3,6′- and 1,6′-Dithiopomalidomide Mitigate Ischemic Stroke in Rats and Blunt Inflammation.
Published in:
Pharmaceutics, 2022, v. 14, n. 5, p. 950, doi. 10.3390/pharmaceutics14050950
By:
- Tsai, Yan-Rou;
- Kim, Dong Seok;
- Hsueh, Shih-Chang;
- Chen, Kai-Yun;
- Wu, John Chung-Che;
- Wang, Jia-Yi;
- Tsou, Yi-Syue;
- Hwang, Inho;
- Kim, Yukyung;
- Gil, Dayeon;
- Jo, Eui Jung;
- Han, Baek-Soo;
- Tweedie, David;
- Lecca, Daniela;
- Scerba, Michael T.;
- Selman, Warren R.;
- Hoffer, Barry J.;
- Greig, Nigel H.;
- Chiang, Yung-Hsiao
Publication type:
Article
Nuclear ERK1/2 signaling potentiation enhances neuroprotection and cognition via Importinα1/KPNA2.
Published in:
EMBO Molecular Medicine, 2023, v. 15, n. 11, p. 1, doi. 10.15252/emmm.202215984
By:
- Indrigo, Marzia;
- Morella, Ilaria;
- Orellana, Daniel;
- d'Isa, Raffaele;
- Papale, Alessandro;
- Parra, Riccardo;
- Gurgone, Antonia;
- Lecca, Daniela;
- Cavaccini, Anna;
- Tigaret, Cezar M;
- Cagnotto, Alfredo;
- Jones, Kimberley;
- Brooks, Simon;
- Ratto, Gian Michele;
- Allen, Nicholas D;
- Lelos, Mariah J;
- Middei, Silvia;
- Giustetto, Maurizio;
- Carta, Anna R;
- Tonini, Raffaella
Publication type:
Article
(−)‐Phenserine tartrate (PhenT) as a treatment for traumatic brain injury.
Published in:
CNS Neuroscience & Therapeutics, 2020, v. 26, n. 6, p. 636, doi. 10.1111/cns.13274
By:
- Greig, Nigel H.;
- Lecca, Daniela;
- Hsueh, Shih‐Chang;
- Nogueras‐Ortiz, Carlos;
- Kapogiannis, Dimitrios;
- Tweedie, David;
- Glotfelty, Elliot J.;
- Becker, Robert E.;
- Chiang, Yung‐Hsiao;
- Hoffer, Barry J.
Publication type:
Article
Mitigating chronic neuroinflammation in Alzheimer mice by novel immunomodulatory imide drugs (IMiDs) conserves neuroplasticity and cognitive function and also alleviates neurodegeneration‐behavioral impairments in TBI‐challenged mice.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 21, p. 1, doi. 10.1002/alz.080689
By:
- Greig, Nigel H;
- Lecca, Daniela;
- Hsueh, Shih Chang;
- Tweedie, David;
- Scerba, Michael T;
- Hoffer, Barry;
- Wang, Jia‐Yi;
- Sambamurti, Kumar;
- Lahiri, Debomoy K.;
- Kim, Dong Seok
Publication type:
Article
Targeting neuroinflammation reduces synaptic, neuronal and cognitive loss in 5xFAD Alzheimer mice.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 10, p. 1, doi. 10.1002/alz.061558
By:
- Lecca, Daniela;
- Yung, Yoo Jin;
- Scerba, Michael T;
- Tweedie, David;
- Hsueh, Shih Chang;
- Hoffer, Barry;
- Kim, Dong Seok;
- McDevitt, Ross A;
- Greig, Nigel H
Publication type:
Article
Role of chronic neuroinflammation in neuroplasticity and cognitive function: A hypothesis.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 11, p. 2327, doi. 10.1002/alz.12610
By:
- Lecca, Daniela;
- Jung, Yoo Jin;
- Scerba, Michael T.;
- Hwang, Inho;
- Kim, Yu Kyung;
- Kim, Sun;
- Modrow, Sydney;
- Tweedie, David;
- Hsueh, Shih‐Chang;
- Liu, Dong;
- Luo, Weiming;
- Glotfelty, Elliot;
- Li, Yazhou;
- Wang, Jia‐Yi;
- Luo, Yu;
- Hoffer, Barry J.;
- Kim, Dong Seok;
- McDevitt, Ross A.;
- Greig, Nigel H.
Publication type:
Article
P3‐056: PROTECTIVE EFFECTS OF (‐)‐PHENSERINE (PHEN) IN ALZHEIMER'S DISEASE (AD) AND MILD TRAUMATIC BRAIN INJURY (MTBI) MURINE MODELS.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P947, doi. 10.1016/j.jalz.2019.06.3083
By:
- Lecca, Daniela;
- Bader, Miaad;
- Tweedie, David;
- Lahiri, Debomoy K.;
- Becker, Robert E.;
- Pick, Chaim;
- Hoffman, Alexander F.;
- Lupica, Carl R.;
- Greig, Nigel H.
Publication type:
Article
P3‐053: (‐)‐PHENSERINE (PHEN) AND THE PREVENTION OF PRE‐PROGRAMMED CELL DEATH IN ALZHEIMER'S DISEASE (AD) AND MILD TRAUMATIC BRAIN INJURY (MTBI).
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1083, doi. 10.1016/j.jalz.2018.06.1409
By:
- Lecca, Daniela;
- Bader, Miaad;
- Tweedie, David;
- Lahiri, Debomoy K.;
- Becker, Robert E.;
- Pick, Chaim;
- Greig, Nigel H.
Publication type:
Article
3,6′-Dithiopomalidomide Ameliorates Hippocampal Neurodegeneration, Microgliosis and Astrogliosis and Improves Cognitive Behaviors in Rats with a Moderate Traumatic Brain Injury.
Published in:
International Journal of Molecular Sciences, 2021, v. 22, n. 15, p. 8276, doi. 10.3390/ijms22158276
By:
- Huang, Pen-Sen;
- Tsai, Ping-Yen;
- Yang, Ling-Yu;
- Lecca, Daniela;
- Luo, Weiming;
- Kim, Dong Seok;
- Hoffer, Barry J.;
- Chiang, Yung-Hsiao;
- Greig, Nigel H.;
- Wang, Jia-Yi
Publication type:
Article
Novel, thalidomide-like, non-cereblon binding drug tetrafluorobornylphthalimide mitigates inflammation and brain injury.
Published in:
Journal of Biomedical Science, 2023, v. 30, n. 1, p. 1, doi. 10.1186/s12929-023-00907-5
By:
- Lecca, Daniela;
- Hsueh, Shih-Chang;
- Luo, Weiming;
- Tweedie, David;
- Kim, Dong Seok;
- Baig, Abdul Mannan;
- Vargesson, Neil;
- Kim, Yu Kyung;
- Hwang, Inho;
- Kim, Sun;
- Hoffer, Barry J.;
- Chiang, Yung-Hsiao;
- Greig, Nigel H.
Publication type:
Article
Chronic inflammation with microglia senescence at basal forebrain: impact on cholinergic deficit in Alzheimer's brain haemodynamics.
Published in:
Brain Communications, 2024, v. 6, n. 4, p. 1, doi. 10.1093/braincomms/fcae204
By:
- Liu, Dong;
- Hsueh, Shih Chang;
- Tweedie, David;
- Price, Nate;
- Glotfelty, Elliot;
- Lecca, Daniela;
- Telljohann, Richard;
- deCabo, Rafael;
- Hoffer, Barry J;
- Greig, Nigel H
Publication type:
Article
Boosting phagocytosis and anti-inflammatory phenotype in microglia mediates neuroprotection by PPARγ agonist MDG548 in Parkinson's disease models.
Published in:
2018
By:
- Lecca, Daniela;
- Janda, Elzbieta;
- Mulas, Giovanna;
- Diana, Andrea;
- Martino, Concetta;
- Angius, Fabrizio;
- Spolitu, Stefano;
- Casu, Maria Antonietta;
- Simbula, Gabriella;
- Boi, Laura;
- Batetta, Barbara;
- Spiga, Saturnino;
- Carta, Anna R.
Publication type:
journal article
Activity of a Novel Anti-Inflammatory Agent F-3,6′-dithiopomalidomide as a Treatment for Traumatic Brain Injury.
Published in:
Biomedicines, 2022, v. 10, n. 10, p. N.PAG, doi. 10.3390/biomedicines10102449
By:
- Hsueh, Shih Chang;
- Scerba, Michael T.;
- Tweedie, David;
- Lecca, Daniela;
- Kim, Dong Seok;
- Baig, Abdul Mannan;
- Kim, Yu Kyung;
- Hwang, Inho;
- Kim, Sun;
- Selman, Warren R.;
- Hoffer, Barry J.;
- Greig, Nigel H.
Publication type:
Article
Microglia Drive Pockets of Neuroinflammation in Middle Age.
Published in:
Journal of Neuroscience, 2022, v. 42, n. 19, p. 3896, doi. 10.1523/JNEUROSCI.1922-21.2022
By:
- Moca, Eric N.;
- Lecca, Daniela;
- Hope, Keenan T.;
- Etienne, Fanny;
- Schaler, Ari W.;
- Espinoza, Katherine;
- Chappell, Megan S.;
- Gray, Daniel T.;
- Tweedie, David;
- Sidhu, Shanaya;
- Masukawa, Lindsay;
- Sitoy, Hannah;
- Mathew, Rose;
- Saban, Daniel R.;
- Greig, Nigel H.;
- De Biase, Lindsay M.
Publication type:
Article
Author Correction: Post-treatment with PT302, a long-acting Exendin-4 sustained release formulation, reduces dopaminergic neurodegeneration in a 6-Hydroxydopamine rat model of Parkinson’s disease.
Published in:
Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-31455-w
By:
- Chen, Shuchun;
- Yu, Seong-Jin;
- Li, Yazhou;
- Lecca, Daniela;
- Glotfelty, Elliot;
- Kim, Hee Kyung;
- Choi, Ho-Il;
- Hoffer, Barry J.;
- Greig, Nigel H.;
- Kim, Dong Seok;
- Wang, Yun
Publication type:
Article

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