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Common polygenic variation enhances risk prediction for Alzheimer's disease.
Published in:
2015
By:
- Escott-Price, Valentina;
- Sims, Rebecca;
- Bannister, Christian;
- Harold, Denise;
- Vronskaya, Maria;
- Majounie, Elisa;
- Badarinarayan, Nandini;
- Morgan, Kevin;
- Passmore, Peter;
- Holmes, Clive;
- Powell, John;
- Brayne, Carol;
- Gill, Michael;
- Mead, Simon;
- Goate, Alison;
- Cruchaga, Carlos;
- Lambert, Jean-Charles;
- van Duijn, Cornelia;
- Maier, Wolfgang;
- Ramirez, Alfredo
Publication type:
journal article
P3‐128: THE INFLUENCE OF IMMUNE, ENDOCYTOTIC AND LIPID METABOLISM GENES ON CYTOKINES AND GLUCOSE METABOLISM IN SUBJECTS WITH MILD COGNITIVE IMPAIRMENT.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P980, doi. 10.1016/j.jalz.2019.06.3156
By:
- van der Thiel, Merel;
- Femminella, Grazia Daniela;
- Harold, Denise;
- Scott, James;
- Williams, Julie;
- Edison, Paul
Publication type:
Article
O2‐15‐01: THE DIFFERENTIAL INFLUENCE OF IMMUNE, ENDOCYTOTIC AND LIPID METABOLISM GENES ON AMYLOID DEPOSITION AND NEURODEGENERATION IN ALZHEIMER'S DISEASE.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P659, doi. 10.1016/j.jalz.2018.06.2724
By:
- Femminella, Grazia Daniela;
- Talib, Sophie;
- Harold, Denise;
- Williams, Julie;
- Edison, Paul
Publication type:
Article
Effects of complement gene‐set polygenic risk score on brain volume and cortical measures in patients with psychotic disorders and healthy controls.
Published in:
American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 2020, v. 183, n. 8, p. 445, doi. 10.1002/ajmg.b.32820
By:
- Holland, Jessica F.;
- Cosgrove, Donna;
- Whitton, Laura;
- Harold, Denise;
- Corvin, Aiden;
- Gill, Michael;
- Mothersill, David O.;
- Morris, Derek W.;
- Donohoe, Gary
Publication type:
Article
Population‐based identity‐by‐descent mapping combined with exome sequencing to detect rare risk variants for schizophrenia.
Published in:
American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 2019, v. 180, n. 3, p. 223, doi. 10.1002/ajmg.b.32716
By:
- Harold, Denise;
- Connolly, Siobhan;
- Riley, Brien P.;
- Kendler, Kenneth S.;
- McCarthy, Shane E.;
- McCombie, William R.;
- Richards, Alex;
- Owen, Michael J.;
- O'Donovan, Michael C.;
- Walters, James;
- Donnelly, Peter;
- Bates, Lesley;
- Barroso, Ines;
- Blackwell, Jenefer M.;
- Bramon, Elvira;
- Brown, Matthew A.;
- Casas, Juan P.;
- Corvin, Aiden;
- Deloukas, Panos;
- Duncanson, Audrey
Publication type:
Article
Effects of MiR‐137 genetic risk score on brain volume and cortical measures in patients with schizophrenia and controls.
Published in:
American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 2018, v. 177, n. 3, p. 369, doi. 10.1002/ajmg.b.32620
By:
- Cosgrove, Donna;
- Mothersill, David O.;
- Whitton, Laura;
- Harold, Denise;
- Kelly, Sinead;
- Holleran, Laurena;
- Holland, Jessica;
- Anney, Richard;
- The Wellcome Trust Case Control Consortium;
- Richards, Alex;
- Mantripragada, Kiran;
- Owen, Michael;
- O'Donovan, Michael C.;
- Gill, Michael;
- Corvin, Aiden;
- Morris, Derek W.;
- Donohoe, Gary
Publication type:
Article
Cognitive analysis of schizophrenia risk genes that function as epigenetic regulators of gene expression.
Published in:
American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 2016, v. 171B, n. 8, p. 1170, doi. 10.1002/ajmg.b.32503
By:
- Whitton, Laura;
- Cosgrove, Donna;
- Clarkson, Christopher;
- Harold, Denise;
- Kendall, Kimberley;
- Richards, Alex;
- Mantripragada, Kiran;
- Owen, Michael J.;
- O'Donovan, Michael C.;
- Walters, James;
- Hartmann, Annette;
- Konte, Betina;
- Rujescu, Dan;
- Gill, Michael;
- Corvin, Aiden;
- Rea, Stephen;
- Donohoe, Gary;
- Morris, Derek W.
Publication type:
Article
Genetic variation at the CELF1 (CUGBP, elav-like family member 1 gene) locus is genome-wide associated with Alzheimer's disease and obesity.
Published in:
American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 2014, v. 165B, n. 4, p. 283, doi. 10.1002/ajmg.b.32234
By:
- Hinney, Anke;
- Albayrak, Özgür;
- Antel, Jochen;
- Volckmar, Anna‐Lena;
- Sims, Rebecca;
- Chapman, Jade;
- Harold, Denise;
- Gerrish, Amy;
- Heid, Iris M.;
- Winkler, Thomas W.;
- Scherag, André;
- Wiltfang, Jens;
- Williams, Julie;
- Hebebrand, Johannes
Publication type:
Article
A COMMON ALLELE IN SPI1 LOWERS RISK AND DELAYS AGE AT ONSET FOR ALZHEIMER'S DISEASE.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P253, doi. 10.1016/j.jalz.2016.06.453
By:
- Huang, Kuan-Lin;
- Jin, Sheng Chih;
- Harari, Oscar;
- Kapoor, Manav;
- Bertelsen, Sarah;
- Czajkowski, Jake;
- Lambert, jean-Charles;
- Chouraki, Vincent;
- Bellenguez, Céline;
- Grenier-Boley, Benjamin;
- Deming, Yuetiva;
- McKenzie, Andrew;
- Renton, Alan E.;
- Budde, John;
- Del-Aguila, Jorge L.;
- Fernandez, Maria Victoria;
- Ibanez, Laura;
- Harold, Denise;
- Hollingworth, Paul;
- Mayeux, Richard
Publication type:
Article
Using polygenic risk score to predict Alzheimer’s disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P872, doi. 10.1016/j.jalz.2015.08.069
By:
- Escott-Price, Valentina;
- Sims, Rebecca;
- Harold, Denise;
- Vronskaya, Maria;
- Holmans, Peter;
- Williams, Julie
Publication type:
Article
Alzheimer's disease with agitation: A genome-wide association study
Published in:
2012
By:
- Chapman, Jade;
- Sims, Rebecca;
- Harold, Denise;
- Gerrish, Amy;
- Hollingworth, Paul;
- Williams, Julie
Publication type:
Abstract
Genome-wide association study of Alzheimer's disease with depressive symptoms
Published in:
2012
By:
- Harold, Denise
Publication type:
Abstract
Genome-Wide Association Study for Alzheimer’s Disease with Psychotic Symptoms
Published in:
2011
By:
- Hollingworth, Paul;
- Sweet, Robert;
- Sims, Rebecca;
- Harold, Denise;
- Abraham, Richard;
- Gerrish, Amy;
- Devlin, Bernie;
- Klei, Lambertus;
- Barmada, Michael;
- Demirci, Yesim;
- DeKosky, Steven;
- Lopez, Oscar;
- Peter Passmore;
- Mayeux, Richard;
- Kamboh, Ilyas;
- Williams, Julie
Publication type:
Abstract
Genome-wide association studies using prospective cohorts: The CHARGE consortium
Published in:
2011
By:
- DeStefano, Anita;
- Seshadri, Sudha;
- Fitzpatrick, Annette;
- Ikram, Mohammad;
- Gudnason, Vilmundur;
- Boada, Merce;
- Williams, Julie;
- Amouyel, Philippe;
- Younkin, Steven;
- Wolf, Philip;
- Launer, Lenore;
- Lopez, Oscar;
- Van Duijn, Cornelia;
- Breteler, Monique;
- Carrasquillo, Minerva;
- Lambert, Jean-Charles;
- Harold, Denise;
- Ruiz, Agustin
Publication type:
Abstract
An examination of APP, PSEN1, PSEN2 and MAPT within a large genome-wide association dataset
Published in:
2010
By:
- Gerrish, Amy;
- Chapman, Jade;
- Harold, Denise;
- Sims, Rebecca;
- Hollingworth, Paul;
- Abraham, Richard
Publication type:
Abstract
Mitochondrial Genome-Wide association study of Alzheimer's disease
Published in:
2010
By:
- Sims, Rebecca;
- Harold, Denise;
- Gerrish, Amy;
- Hollingworth, Paul;
- Abraham, Richard;
- Donovan, Michael O.;
- Owen, Michael;
- Williams, Julie
Publication type:
Abstract
SNPs associated with CSF tau levels modify rate of progression in Alzheimer's disease
Published in:
2010
By:
- Cruchaga, Carlos;
- Kauwe, John S.;
- Mayo, Kevin;
- Bertelsen, Sarah;
- Nowotny, Petra;
- Shah, Aarti R.;
- Abraham, Richard;
- Hollingworth, Paul;
- Harold, Denise;
- Owen, Michael J.;
- Williams, Julie;
- Lovestone, Simon;
- Morris, John C.;
- Fagan, Anne M.;
- Holtzman, David M.;
- Goate, Alison M.
Publication type:
Abstract
Genetic evidence implicates the immune system and cholesterol metabolism in the etiology of Alzheimer's disease
Published in:
2010
By:
- Jones, Lesley;
- Holmans, Peter A.;
- Marian, Hamshere;
- Harold, Denise;
- Moskvina, Valentina;
- Ivanov, Dobril;
- Hardy, John;
- O'Donovan, Michael C.;
- Owen, Michael;
- Williams, Julie
Publication type:
Abstract
Meta-analysis of the association between SORL1 variants and Alzheimer's disease
Published in:
2010
By:
- Reitz, Christiane;
- Cheng, Rong;
- Rogaeva, Ekaterina;
- Lee, Joseph;
- Tokuhiro, Shinya;
- Bettens, Karolien;
- Sleegers, Kristel;
- Tan, Eng King;
- Kimura, Ryo;
- Shibata, Nobuto;
- Kamboh, Ilyas M.;
- Prince, Jonathan;
- Maier, Wolfgang;
- Riemenschneider, Matthias;
- Owen, Michael;
- Harold, Denise;
- Hollingworth, Paul;
- Cellini, Elena;
- Pericak-Vance, Margaret A.;
- Younkin, Steven
Publication type:
Abstract
New susceptibility genes identified for Alzheimer's disease: Progress from the GERAD (genetic and environmental risk in Alzheimer's disease) consortium
Published in:
2010
By:
- Harold, Denise
Publication type:
Abstract
Genome-wide association study of age at onset of Alzheimer's disease
Published in:
2009
By:
- Harold, Denise;
- Hollingworth, Paul;
- Hamshere, Marian;
- Holmans, Peter;
- Abraham, Richard;
- Sims, Rebecca;
- Gerrish, Amy;
- Lovestone, Simon;
- Brayne, Carol;
- Gill, Michael;
- Lawlor, Brian;
- Passmore, Peter;
- Nothen, Markus;
- Maier, Wolfgang;
- Livingston, Gill;
- Bass, Nicola;
- Goate, Alison;
- Younkin, Steven;
- Al-Chalabi, Ammar;
- Gwilliam, Rhian
Publication type:
Abstract
An examination of previously reported Alzheimer candidate genes within a large genome-wide association dataset
Published in:
2009
By:
- Gerrish, Amy;
- Harold, Denise;
- Sims, Rebecca;
- Abraham, Richard;
- Hollingworth, Paul;
- Hamshere, Marian;
- Lovestone, Simon;
- Brayne, Carol;
- Gill, Michael;
- Lawlor, Brian;
- Passmore, Peter;
- Nothen, Markus;
- Mayer, Wolfgang;
- Livingston, Gill;
- Bass, Nicolas;
- Goate, Alison;
- Younkin, Steve;
- Al-Chalabi, Ammar;
- Gwilliam, Rhian;
- Morgan, Kevin
Publication type:
Abstract
Genome-wide association study of Alzheimer's with psychotic symptoms
Published in:
2009
By:
- Hollingworth, Paul;
- Sims, Rebecca;
- Abraham, Richard;
- Harold, Denise;
- Gerrish, Amy;
- Hamshere, Marian;
- Lovestone, Simon;
- Brayne, Carol;
- Gill, Michael;
- Lawlor, Brian;
- Passmore, Peter;
- Nothen, Markus;
- Mayer, Wolfgang;
- Livingston, Gill;
- Bass, Nicolas;
- Goate, Alison;
- Younkin, Steve;
- Al-Chalabi, Ammar;
- Gwilliam, Rhian;
- Morgan, Kevin
Publication type:
Abstract
Investigating psychosis candidate genes in Alzheimer's disease with psychosis using genome-wide association studies
Published in:
2009
By:
- Sims, Rebecca;
- Hollingworth, Paul;
- Abraham, Richard;
- Harold, Denise;
- Holmans, Peter;
- Lovestone, Simon;
- Powell, John;
- Brayne, Carol;
- Rubinsztein, David C.;
- Gill, Mike;
- Lawlor, Brian;
- Craig, David;
- Passmore, Peter;
- Nöthen, Marcus;
- Mayer, Wolfgang;
- Livingston, Gill;
- Bass, Nicolas;
- Goate, Alison;
- Morgan, Kevin;
- Smith, David
Publication type:
Abstract
Testing for association between Alzheimer's disease and known susceptibility variants for type 2 diabetes
Published in:
2009
By:
- Stretton, Alexandra;
- Sims, Rebecca;
- Harold, Denise;
- Abraham, Richard;
- Hollingworth, Paul;
- Dowzell, Kimberly;
- Jones, Nicola;
- Williams, Amy;
- Owen, Michael;
- Williams, Julie
Publication type:
Abstract
P1-332: Glycogen synthase kinase -3 beta polymorphisms interact with Tau haplotypes in Alzheimer’s disease
Published in:
2006
By:
- Kwok, John B.;
- Hallupp, Marianne;
- Loy, Clement T.;
- Harold, Denise H.;
- Williams, Julie;
- Owen, Michael J.;
- Lovestone, Simon;
- Powell, John;
- Broe, G. Anthony;
- Schofield, Peter R.
Publication type:
Abstract
P1-328: Association analysis of 22 positional/functional candidate genes on chromosome 10 with late onset Alzheimer’s disease
Published in:
2006
By:
- Morgan, Angharad R.;
- Jehu, Luke;
- Turic, Dragana;
- Harold, Denise;
- Hamilton, Gillian;
- Hollingworth, Paul;
- Moore, Pamela;
- Dowzell, Kimberley;
- Moskvina, Valentina;
- Jones, Lesley;
- Powell, John;
- Lovestone, Simon;
- Brayne, Carol;
- Rubinsztein, David C.;
- O’Donovan, Michael;
- Owen, Mike J.;
- Williams, Julie
Publication type:
Abstract
P1-284: Interaction between ADAM12 and SH3MD1 may confer susceptibility to late-onset Alzheimer’s disease
Published in:
2006
By:
- Williams, Julie;
- Harold, Denise;
- Jehu, Luke;
- Turic, Dragana;
- Hollingworth, Paul;
- Moskvina, Valentina;
- Brayne, Carol;
- Rubensztein, David;
- Lovestone, Simon;
- Powell, John;
- Jones, Lesley;
- O’Donovan, Michael;
- Owen, Michael
Publication type:
Abstract
P1-275: A single nucleotide polymorphism in CHAT influences response to acetylcholinesterase inhibitors in Alzheimer’s disease
Published in:
2006
By:
- Jones, Lesley;
- Harold, Denise;
- MacGregor, Stuart;
- Patterson, Cathryn E.;
- Hollingworth, Paul;
- Owen, Michael J.;
- Williams, Julie;
- McIlroy, Stephen;
- Passmore, Peter;
- O’Donovan, Michael
Publication type:
Abstract
P1-332: Glycogen synthase kinase -3 beta polymorphisms interact with Tau haplotypes in Alzheimer’s disease
Published in:
2006
By:
- Kwok, John B.;
- Hallupp, Marianne;
- Loy, Clement T.;
- Harold, Denise H.;
- Williams, Julie;
- Owen, Michael J.;
- Lovestone, Simon;
- Powell, John;
- Broe, G. Anthony;
- Schofield, Peter R.
Publication type:
Abstract
P1-328: Association analysis of 22 positional/functional candidate genes on chromosome 10 with late onset Alzheimer’s disease
Published in:
2006
By:
- Morgan, Angharad R.;
- Jehu, Luke;
- Turic, Dragana;
- Harold, Denise;
- Hamilton, Gillian;
- Hollingworth, Paul;
- Moore, Pamela;
- Dowzell, Kimberley;
- Moskvina, Valentina;
- Jones, Lesley;
- Powell, John;
- Lovestone, Simon;
- Brayne, Carol;
- Rubinsztein, David C.;
- O’Donovan, Michael;
- Owen, Mike J.;
- Williams, Julie
Publication type:
Abstract
P1-284: Interaction between ADAM12 and SH3MD1 may confer susceptibility to late-onset Alzheimer’s disease
Published in:
2006
By:
- Williams, Julie;
- Harold, Denise;
- Jehu, Luke;
- Turic, Dragana;
- Hollingworth, Paul;
- Moskvina, Valentina;
- Brayne, Carol;
- Rubensztein, David;
- Lovestone, Simon;
- Powell, John;
- Jones, Lesley;
- O’Donovan, Michael;
- Owen, Michael
Publication type:
Abstract
P1-275: A single nucleotide polymorphism in CHAT influences response to acetylcholinesterase inhibitors in Alzheimer’s disease
Published in:
2006
By:
- Jones, Lesley;
- Harold, Denise;
- MacGregor, Stuart;
- Patterson, Cathryn E.;
- Hollingworth, Paul;
- Owen, Michael J.;
- Williams, Julie;
- McIlroy, Stephen;
- Passmore, Peter;
- O’Donovan, Michael
Publication type:
Abstract
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
Published in:
Nature Genetics, 2013, v. 45, n. 12, p. 1452, doi. 10.1038/ng.2802
By:
- Lambert, Jean-Charles;
- Ibrahim-Verbaas, Carla A;
- Harold, Denise;
- Naj, Adam C;
- Sims, Rebecca;
- Bellenguez, Céline;
- Jun, Gyungah;
- DeStefano, Anita L;
- Bis, Joshua C;
- Beecham, Gary W;
- Grenier-Boley, Benjamin;
- Russo, Giancarlo;
- Thornton-Wells, Tricia A;
- Jones, Nicola;
- Smith, Albert V;
- Chouraki, Vincent;
- Thomas, Charlene;
- Ikram, M Arfan;
- Zelenika, Diana;
- Vardarajan, Badri N
Publication type:
Article
Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease.
Published in:
Nature Genetics, 2013, v. 45, n. 6, p. 712, doi. 10.1038/ng0613-712a
By:
- Harold, Denise;
- Abraham, Richard;
- Hollingworth, Paul;
- Sims, Rebecca;
- Gerrish, Amy;
- Hamshere, Marian L;
- Pahwa, Jaspreet Singh;
- Moskvina, Valentina;
- Dowzell, Kimberley;
- Williams, Amy;
- Jones, Nicola;
- Thomas, Charlene;
- Stretton, Alexandra;
- Morgan, Angharad R;
- Lovestone, Simon;
- Powell, John;
- Proitsi, Petroula;
- Lupton, Michelle K;
- Brayne, Carol;
- Rubinsztein, David C
Publication type:
Article
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease.
Published in:
Nature Genetics, 2011, v. 43, n. 5, p. 429, doi. 10.1038/ng.803
By:
- Hollingworth, Paul;
- Harold, Denise;
- Sims, Rebecca;
- Gerrish, Amy;
- Lambert, Jean-Charles;
- Carrasquillo, Minerva M.;
- Abraham, Richard;
- Hamshere, Marian L.;
- Pahwa, Jaspreet Singh;
- Moskvina, Valentina;
- Dowzell, Kimberley;
- Jones, Nicola;
- Stretton, Alexandra;
- Thomas, Charlene;
- Richards, Alex;
- Ivanov, Dobril;
- Widdowson, Caroline;
- Chapman, Jade;
- Lovestone, Simon;
- Powell, John
Publication type:
Article
Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease.
Published in:
Nature Genetics, 2009, v. 41, n. 10, p. 1088, doi. 10.1038/ng.440
By:
- Harold, Denise;
- Abraham, Richard;
- Hollingworth, Paul;
- Sims, Rebecca;
- Gerrish, Amy;
- Hamshere, Marian L.;
- Pahwa, Jaspreet Singh;
- Moskvina, Valentina;
- Dowzell, Kimberley;
- Williams, Amy;
- Jones, Nicola;
- Thomas, Charlene;
- Stretton, Alexandra;
- Morgan, Angharad R.;
- Lovestone, Simon;
- Powell, John;
- Proitsi, Petroula;
- Lupton, Michelle K.;
- Brayne, Carol;
- Rubinsztein, David C.
Publication type:
Article
Erratum: Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease.
Published in:
2009
By:
- Harold, Denise;
- Abraham, Richard;
- Hollingworth, Paul;
- Sims, Rebecca;
- Gerrish, Amy;
- Hamshere, Marian L.;
- Pahwa, Jaspreet Singh;
- Moskvina, Valentina;
- Dowzell, Kimberley;
- Williams, Amy;
- Jones, Nicola;
- Thomas, Charlene;
- Stretton, Alexandra;
- Morgan, Angharad R.;
- Lovestone, Simon;
- Powell, John;
- Proitsi, Petroula;
- Lupton, Michelle K.;
- Brayne, Carol;
- Rubinsztein, David C.
Publication type:
Correction Notice
Beyond C4: Analysis of the complement gene pathway shows enrichment for IQ in patients with psychotic disorders and healthy controls.
Published in:
Genes, Brain & Behavior, 2019, v. 18, n. 8, p. N.PAG, doi. 10.1111/gbb.12602
By:
- Holland, Jessica F.;
- Cosgrove, Donna;
- Whitton, Laura;
- Harold, Denise;
- Corvin, Aiden;
- Gill, Michael;
- Mothersill, David O.;
- Morris, Derek W.;
- Donohoe, Gary
Publication type:
Article
Gene-Wide Analysis Detects Two New Susceptibility Genes for Alzheimer's Disease.
Published in:
PLoS ONE, 2014, v. 9, n. 6, p. 1, doi. 10.1371/journal.pone.0094661
By:
- Escott-Price, Valentina;
- Bellenguez, Céline;
- Wang, Li-San;
- Choi, Seung-Hoan;
- Harold, Denise;
- Jones, Lesley;
- Holmans, Peter;
- Gerrish, Amy;
- Vedernikov, Alexey;
- Richards, Alexander;
- DeStefano, Anita L.;
- Lambert, Jean-Charles;
- Ibrahim-Verbaas, Carla A.;
- Naj, Adam C.;
- Sims, Rebecca;
- Jun, Gyungah;
- Bis, Joshua C.;
- Beecham, Gary W.;
- Grenier-Boley, Benjamin;
- Russo, Giancarlo
Publication type:
Article
Characterisation and Validation of Insertions and Deletions in 173 Patient Exomes.
Published in:
PLoS ONE, 2012, v. 7, n. 12, p. 1, doi. 10.1371/journal.pone.0051292
By:
- Lescai, Francesco;
- Bonfiglio, Silvia;
- Bacchelli, Chiara;
- Chanudet, Estelle;
- Waters, Aoife;
- Sisodiya, Sanjay M.;
- Kasperavičiū tė, Dalia;
- Williams, Julie;
- Harold, Denise;
- Hardy, John;
- Kleta, Robert;
- Cirak, Sebahattin;
- Williams, Richard;
- Achermann, John C.;
- Anderson, John;
- Kelsell, David;
- Vulliamy, Tom;
- Houlden, Henry;
- Wood, Nicholas;
- Sheerin, Una
Publication type:
Article
eep Sequencing of the Nicastrin Gene in Pooled DNA, the Identification of Genetic Variants That Affect Risk of Alzheimer's Disease.
Published in:
PLoS ONE, 2011, v. 6, n. 2, p. 1, doi. 10.1371/journal.pone.0017298
By:
- Lupton, Michelle K.;
- Proitsi, Petroula;
- Danillidou, Makrina;
- Tsolaki, Magda;
- Hamilton, Gillian;
- Wroe, Richard;
- Pritchard, Megan;
- Lord, Kathryn;
- Martin, Belinda M.;
- Kloszewska, Iwona;
- Soininen, Hilkka;
- Mecocci, Patrizia;
- Vellas, Bruno;
- Harold, Denise;
- Hollingworth, Paul;
- Lovestone, Simon;
- Powell, John F.
Publication type:
Article
Genetic Evidence Implicates the Immune System and Cholesterol Metabolism in the Aetiology of Alzheimer's Disease.
Published in:
PLoS ONE, 2010, v. 5, n. 11, p. 1, doi. 10.1371/journal.pone.0013950
By:
- Jones, Lesley;
- Holmans, Peter A.;
- Hamshere, Marian L.;
- Harold, Denise;
- Moskvina, Valentina;
- Ivanov, Dobril;
- Pocklington, Andrew;
- Abraham, Richard;
- Hollingworth, Paul;
- Sims, Rebecca;
- Gerrish, Amy;
- Pahwa, Jaspreet Singh;
- Jones, Nicola;
- Stretton, Alexandra;
- Morgan, Angharad R.;
- Lovestone, Simon;
- Powell, John;
- Proitsi, Petroula;
- Lupton, Michelle K.;
- Brayne, Carol
Publication type:
Article
Sequence variation in the CHAT locus shows no association with late-onset Alzheimer's disease.
Published in:
Human Genetics, 2003, v. 113, n. 3, p. 258, doi. 10.1007/s00439-003-0960-2
By:
- Harold, Denise;
- Peirce, Timothy;
- Moskvina, Valentina;
- Myers, Amanda;
- Jones, Susan;
- Hollingworth, Paul;
- Moore, Pamela;
- Lovestone, Simon;
- Powell, John;
- Foy, Catherine;
- Archer, Nicola;
- Walter, Sarah;
- Edmonson, Amanda;
- McIlroy, Stephen;
- Craig, David;
- Passmore, Peter A.;
- Goate, Alison;
- Hardy, John;
- O'Donovan, Michael;
- Williams, Julie
Publication type:
Article
Analysis of Genome-Wide Association Studies of Alzheimer Disease and of Parkinson Disease to Determine If These 2 Diseases Share a Common Genetic Risk.
Published in:
JAMA Neurology, 2013, v. 70, n. 10, p. 1268, doi. 10.1001/jamaneurol.2013.448
By:
- Moskvina, Valentina;
- Harold, Denise;
- Russo, GianCarlo;
- Vedernikov, Alexey;
- Sharma, Manu;
- Saad, Mohamad;
- Holmans, Peter;
- Bras, Jose M.;
- Bettella, Francesco;
- Keller, Margaux F.;
- Nicolaou, Nayia;
- Simón-Sánchez, Javier;
- Gibbs, J. Raphael;
- Schulte, Claudia;
- Durr, Alexandra;
- Guerreiro, Rita;
- Hernandez, Dena;
- Brice, Alexis;
- Stefánsson, Hreinn;
- Majamaa, Kari
Publication type:
Article
Genome-wide Analysis of Genetic Loci Associated With Alzheimer Disease.
Published in:
JAMA: Journal of the American Medical Association, 2010, v. 303, n. 18, p. 1832, doi. 10.1001/jama.2010.574
By:
- Seshadri, Sudha;
- Fitzpatrick, Annette L.;
- Ikram, M. Arfan;
- DeStefano, Anita L.;
- Gudnason, Vilmundur;
- Boada, Merce;
- Bis, Joshua C.;
- Smith, Albert V.;
- Carassquillo, Minerva M.;
- Lambert, Jean Charles;
- Harold, Denise;
- Schrijvers, Elisabeth M. C.;
- Ramirez-Lorca, Reposo;
- Debette, Stephanie;
- Longstreth Jr., W. T.;
- Janssens, A. Cecile J. W.;
- Pankratz, V. Shane;
- Dartigues, Jean François;
- Hollingworth, Paul;
- Aspelund, Thor
Publication type:
Article
α-T-catenin is expressed in human brain and interacts with the Wnt signaling pathway but is not responsible for linkage to chromosome 10 in Alzheimer’s disease.
Published in:
NeuroMolecular Medicine, 2004, v. 5, n. 2, p. 133, doi. 10.1385/NMM:5:2:133
By:
- Busby, Victoria;
- Goossens, Steven;
- Nowotny, Petra;
- Hamilton, Gillian;
- Smemo, Scott;
- Harold, Denise;
- Turic, Dragana;
- Jehu, Luke;
- Myers, Amanda;
- Womick, Meredith;
- Woo, Daniel;
- Compton, Danielle;
- Doil, Lisa;
- Tacey, Kristina;
- Lau, Kit;
- Al-Saraj, Safa;
- Killick, Richard;
- Pickering-Brown, Stuart;
- Moore, Pamela;
- Hollingworth, Paul
Publication type:
Article
Shared genetic contribution to Ischaemic Stroke and Alzheimer's Disease.
Published in:
2016
By:
- Traylor, Matthew;
- Adib ‐ Samii, Poneh;
- Harold, Denise;
- Dichgans, Martin;
- Williams, Julie;
- Lewis, Cathryn M.;
- Markus, Hugh S.;
- Adib-Samii, Poneh;
- Alzheimer's Disease Neuroimaging Initiative;
- International Stroke Genetics Consortium (ISGC), UK Young Lacunar Stroke DNA resource;
- METASTROKE;
- International Genomics of Alzheimer's Project (IGAP), investigators
Publication type:
journal article
Can Studies of Neuroinflammation in a TSPO Genetic Subgroup (HAB or MAB) Be Applied to the Entire AD Cohort?
Published in:
Journal of Nuclear Medicine, 2015, v. 56, n. 5, p. 707, doi. 10.2967/jnumed.114.149443
By:
- Zhen Fan;
- Harold, Denise;
- Pasqualetti, Giuseppe;
- Williams, Julie;
- Brooks, David J.;
- Edison, Paul
Publication type:
Article
A modifier of Huntington's disease onset at the MLH1 locus.
Published in:
Human Molecular Genetics, 2017, v. 26, n. 19, p. 3859, doi. 10.1093/hmg/ddx286
By:
- Jong-Min Lee;
- Chao, Michael J.;
- Harold, Denise;
- Elneel, Kawther Abu;
- Gillis, Tammy;
- Holmans, Peter;
- Jones, Lesley;
- Orth, Michael;
- Myers, Richard H.;
- Seung Kwa;
- Wheeler, Vanessa C.;
- MacDonald, Marcy E.;
- Gusella, James F.
Publication type:
Article

Found: 55