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- Title
Pertussis in children in the İstanbul Faculty of Medicine: results for four years.
- Authors
Öksüz, Lütfiye; Hançerli, Selda; Somer, Ayper; Salman, Nuran; Gürler, Nezahat
- Abstract
We investigated the frequency of pertussis among children in the İstanbul Faculty of Medicine Hospital during a period of four years. Clinical specimens were obtained from children who exhibited symptoms of whooping cough; a portion of the cases were confirmed microbiologically by PCR as pertussis. A total of 410 nasopharyngeal aspirates were taken for detection of Bordetella pertussis/parapertussis. The age groups of the patients were 0-4 months (n=201), >4 -12 months (n=49), 1-4 years (n=79), 5-9 years (n=46), 10-14 years (n=27) and >15 years (n=8). 106 (26%) of all samples were positive for B. pertussis/parapertussis by the PCR method. The Bordetella PCR positivity rates were 36% in 2010, 29% in 2011, 15% in 2012 and 15% in 2013. Due to administration of the DTaP-IPV vaccination at seven years of age starting in 2010, pertussis was not detected in the 5-9 age group after that year. According to this result, the five doses of pertussis vaccination administered as the national vaccine scheme are effective in protecting against the infection. A booster dose for adolescents at 14 years of age as well as a cocoon strategy might also be considered in our country.
- Subjects
WHOOPING cough; CHILDREN'S health; POLYMERASE chain reaction; AGE groups; WHOOPING cough vaccines; DRUG administration; PATIENTS
- Publication
Turkish Journal of Pediatrics, 2014, Vol 56, Issue 6, p632
- ISSN
0041-4301
- Publication type
Article