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- Title
Acute renal failure SNAPPE and mortality.
- Authors
Türker, Gülcan; Özsoy, Gamze; Günlemez, Ayla; Gökalp, Ayşe S.; Arisoy, Ayşe E.; Bircan, Zelal
- Abstract
Background: The aim of the present study was to determine, using the score for neonatal acute physiology and perinatal extension II (SNAPPE-II), whether there is an association with acute renal failure (ARF) and whether it is possible to identify newborns at risk for ARF prior to a rise in creatinine in newborns. Methods: Information on postnatal risk factors and SNAPPE-II on the first day of life (non-ARF group, n= 475; ARF group, n= 78) were collected. Renal failure was defined as serum creatinine level >1 mg/dL and >1.3 mg/dL (for ≥33 weeks and <33 weeks, respectively) after 48 h of life. Results: In newborns with ARF ( n= 78), the median (range) of SNAPPE-II and mortality rate were significantly higher than those of the control group. Patent ductus arteriosus (PDA), disseminated intravascular coagulation (DIC), SNAPPE-II, and resuscitation were identified as independent predictors of ARF in infants on forward stepwise logistic regression. Sepsis, respiratory distress syndrome, ARF, DIC, and SNAPPE-II were identified as independent predictors of mortality in infants on the same analysis. Conclusions: SNAPPE-II on the first day of life was significantly higher among babies with ARF, suggesting a positive association between higher scores and the development of ARF and mortality, but based on receiver operating characteristic curve results, SNAPPE-II at admission did not enhance the assessment of risk for ARF prior to a rise in creatinine.
- Subjects
CEREBRAL hemorrhage; CHI-squared test; CARDIOPULMONARY resuscitation; CHRONIC kidney failure; CREATININE; DISSEMINATED intravascular coagulation; NEONATAL necrotizing enterocolitis; INFANT mortality; NEONATAL intensive care; PATENT ductus arteriosus; U-statistics; NEONATAL intensive care units; RETROSPECTIVE studies; CASE-control method; RECEIVER operating characteristic curves; DATA analysis software; DISEASE risk factors
- Publication
Pediatrics International, 2011, Vol 53, Issue 4, p483
- ISSN
1328-8067
- Publication type
Article
- DOI
10.1111/j.1442-200X.2011.03377.x