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- Title
Electrospun Nanofibrous Composite Membranes for Long‐Term Release of Celecoxib for Achilles Tendon Reconstruction Following Injury.
- Authors
Yu, Yi‐Hsun; Lee, Chen‐Hung; Hsu, Yung‐Heng; Chou, Ying‐Chao; Yu, Ping‐Chun; Liu, Shih‐Jung
- Abstract
The article titled "Electrospun Nanofibrous Composite Membranes for Long-Term Release of Celecoxib for Achilles Tendon Reconstruction Following Injury" discusses the development of a new implantable combination of nanofibers for Achilles tendon reconstruction. The nanofibers, called celecoxib-collagen-bupivacainepoly(lactic-co-glycolic acid) (CCBP), show improved therapeutic application and higher load-to-failure values compared to healthy tendons and nanofibers with doxycycline. The authors suggest that CCBP is a promising scaffold for repairing ruptured Achilles tendons and is superior to existing materials.
- Subjects
COMPOSITE membranes (Chemistry); ACHILLES tendon; CELECOXIB; ACHILLES tendon rupture; CYCLOOXYGENASE inhibitors; NANOFIBERS; WOUNDS &; injuries
- Publication
Macromolecular Materials & Engineering, 2023, Vol 308, Issue 11, p1
- ISSN
1438-7492
- Publication type
Article
- DOI
10.1002/mame.202300149