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- Title
Hypothermic machine perfusion of kidneys retrieved from standard and high-risk donors.
- Authors
Jochmans, Ina; O'Callaghan, John M.; Pirenne, Jacques; Ploeg, Rutger J.
- Abstract
Hypothermic machine perfusion (HMP) of kidneys is a long-established alternative to static cold storage and has been suggested to be a better preservation method. Today, as our deceased donor profile continues to change towards higher-risk kidneys of lower quality, we are confronted with the limits of cold storage. Interest in HMP as a preservation technique is on the rise. Furthermore, HMP also creates a window of opportunity during which to assess the viability and quality of the graft before transplantation. The technology might also provide a platform during which the graft could be actively repaired, making it particularly attractive for higher-risk kidneys. We review the current evidence on HMP in kidney transplantation and provide an outlook for the use of the technology in the years to come.
- Subjects
PERFUSION; KIDNEY transplantation; TRANSPLANTATION of organs, tissues, etc.; ORGAN donation; PRESERVATION of organs, tissues, etc.; COLD storage
- Publication
Transplant International, 2015, Vol 28, Issue 6, p665
- ISSN
0934-0874
- Publication type
Article
- DOI
10.1111/tri.12530