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- Title
Clinical impact of Prostate-Specific Membrane Antigen Positron Emission Tomography (PET) on intensification or deintensification of advanced renal cell carcinoma management.
- Authors
Pathmanathan, Shivanshan; Tariq, Arsalan; Pearce, Adam; Rhee, Handoo; Kyle, Samuel; Raveenthiran, Sheliyan; Wong, David; McBean, Rhiannon; Marsh, Phillip; Goodman, Steven; Dhiantravan, Nattakorn; Esler, Rachel; Dunglison, Nigel; Navaratnam, Anojan; Yaxley, John; Thomas, Paul; Pattison, David A.; Goh, Jeffrey C.; Gan, Chun Loo; Roberts, Matthew J.
- Abstract
Purpose: There is an emerging role of the use of Prostate-Specific Membrane Antigen (PSMA) Positron Emission Tomography (PET) in renal cell carcinoma. Herein, we report our experience in use of PSMA PET in recurrent or metastatic renal cell carcinoma (RCC). Methods: A retrospective analysis of all patients who underwent PSMA PET for suspected recurrent or de-novo metastatic RCC between 2015 and 2020 at three institutions was performed. The primary outcome was change in management (intensification or de-intensification) following PSMA PET scan. Secondary outcomes included histopathological correlation of PSMA avid sites, comparison of sites of disease on PSMA PET to diagnostic CT and time to systemic treatment. Results:
- Subjects
RENAL cell carcinoma; POSITRON emission tomography
- Publication
European Journal of Nuclear Medicine & Molecular Imaging, 2023, Vol 51, Issue 1, p295
- ISSN
1619-7070
- Publication type
Article
- DOI
10.1007/s00259-023-06380-4