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Large extracellular vesicles carry most of the tumour DNA circulating in prostate cancer patient plasma.
Published in:
Journal of Extracellular Vesicles, 2018, v. 7, n. 1, p. 1, doi. 10.1080/20013078.2018.1505403
By:
- Vagner, Tatyana;
- Spinelli, Cristiana;
- Minciacchi, Valentina R.;
- Balaj, Leonora;
- Zandian, Mandana;
- Conley, Andrew;
- Zijlstra, Andries;
- Freeman, Michael R.;
- Demichelis, Francesca;
- De, Subhajyoti;
- Posadas, Edwin M.;
- Tanaka, Hisashi;
- Di Vizio, Dolores
Publication type:
Article
Large extracellular vesicles carry most of the tumour DNA circulating in prostate cancer patient plasma.
Published in:
Journal of Extracellular Vesicles, 2018, v. 7, n. 1, p. 1, doi. 10.1080/20013078.2018.1505403
By:
- Vagner, Tatyana;
- Spinelli, Cristiana;
- Minciacchi, Valentina R.;
- Balaj, Leonora;
- Zandian, Mandana;
- Conley, Andrew;
- Zijlstra, Andries;
- Freeman, Michael R.;
- Demichelis, Francesca;
- De, Subhajyoti;
- Posadas, Edwin M.;
- Tanaka, Hisashi;
- Di Vizio, Dolores
Publication type:
Article
FYN is overexpressed in human prostate cancer.
Published in:
BJU International, 2009, v. 103, n. 2, p. 171, doi. 10.1111/j.1464-410X.2008.08009.x
By:
- Posadas, Edwin M.;
- Al-Ahmadie, Hikmat;
- Robinson, Victoria L.;
- Jagadeeswaran, Ramasamy;
- Otto, Kristen;
- Kasza, Kristen E.;
- Tretiakov, Maria;
- Siddiqui, Javed;
- Pienta, Kenneth J.;
- Stadler, Walter M.;
- Rinker-Schaeffer, Carrie;
- Salgia, Ravi
Publication type:
Article
Covalent Chemistry‐Mediated Multimarker Purification of Circulating Tumor Cells Enables Noninvasive Detection of Molecular Signatures of Hepatocellular Carcinoma.
Published in:
Advanced Materials Technologies, 2021, v. 6, n. 5, p. 1, doi. 10.1002/admt.202001056
By:
- Sun, Na;
- Lee, Yi‐Te;
- Kim, Minhyung;
- Wang, Jasmine J.;
- Zhang, Ceng;
- Teng, Pai‐Chi;
- Qi, Dongping;
- Zhang, Ryan Y.;
- Tran, Benjamin V.;
- Lee, Yue Tung;
- Ye, Jinglei;
- Palomique, Juvelyn;
- Nissen, Nicholas N.;
- Han, Steven‐Huy B.;
- Sadeghi, Saeed;
- Finn, Richard S.;
- Saab, Sammy;
- Busuttil, Ronald W.;
- Posadas, Edwin M.;
- Liang, Li
Publication type:
Article
Receptor-interacting protein kinase 2 (RIPK2) stabilizes c-Myc and is a therapeutic target in prostate cancer metastasis.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-28340-6
By:
- Yan, Yiwu;
- Zhou, Bo;
- Qian, Chen;
- Vasquez, Alex;
- Kamra, Mohini;
- Chatterjee, Avradip;
- Lee, Yeon-Joo;
- Yuan, Xiaopu;
- Ellis, Leigh;
- Di Vizio, Dolores;
- Posadas, Edwin M.;
- Kyprianou, Natasha;
- Knudsen, Beatrice S.;
- Shah, Kavita;
- Murali, Ramachandran;
- Gertych, Arkadiusz;
- You, Sungyong;
- Freeman, Michael R.;
- Yang, Wei
Publication type:
Article
Detection of Live Circulating Tumor Cells by a Class of Near-Infrared Heptamethine Carbocyanine Dyes in Patients with Localized and Metastatic Prostate Cancer.
Published in:
PLoS ONE, 2014, v. 9, n. 2, p. 1, doi. 10.1371/journal.pone.0088967
By:
- Shao, Chen;
- Liao, Chun-Peng;
- Hu, Peizhen;
- Chu, Chia-Yi;
- Zhang, Lei;
- Bui, Matthew H. T.;
- Ng, Christopher S.;
- Josephson, David Y.;
- Knudsen, Beatrice;
- Tighiouart, Mourad;
- Kim, Hyung L.;
- Zhau, Haiyen E.;
- Chung, Leland W. K.;
- Wang, Ruoxiang;
- Posadas, Edwin M.
Publication type:
Article
Integrating PARP Inhibitors Into Advanced Prostate Cancer Therapeutics.
Published in:
Oncology (08909091), 2021, v. 35, n. 3, p. 119, doi. 10.46883/onc.2021.3503.0119
By:
- Jun Gong;
- Posadas, Edwin M.;
- Bhowmick, Neil;
- Kim, Hyung L.;
- Daskivich, Timothy J.;
- Gupta, Amit;
- Sandler, Howard M.;
- Kamrava, Mitchell;
- Zumsteg, Zachary S.;
- Freedland, Stephen J.;
- Figlin, Robert A.
Publication type:
Article
Third-Line Treatment Options for Kidney Cancer.
Published in:
Oncology (08909091), 2016, v. 30, n. 9, p. 813
By:
- Posadas, Edwin M.;
- Limvorasak, Suwicha;
- Figlin, Robert A.
Publication type:
Article
Systemic Therapy in Renal Cell Carcinoma: Advancing Paradigms.
Published in:
Oncology (08909091), 2012, v. 26, n. 3, p. 290
By:
- Posadas, Edwin M.;
- Figlin, Robert A.
Publication type:
Article
Interleukin 33 supports squamous cell carcinoma growth via a dual effect on tumour proliferation, migration and invasion, and T cell activation.
Published in:
Cancer Immunology, Immunotherapy, 2024, v. 73, n. 6, p. 1, doi. 10.1007/s00262-024-03676-8
By:
- Perri, Graziela;
- Vilas Boas, Vanessa Garcia;
- Nogueira, Maria Renata Sales;
- Mello Júnior, Edgard José Franco;
- Coelho, Ana Lucia;
- Posadas, Edwin M.;
- Hogaboam, Cory;
- Cavassani, Karen A;
- Campanelli, Ana Paula
Publication type:
Article
Intensification of Androgen Deprivation Therapy in High-Risk, Nonmetastatic Prostate Cancer: Lessons From STAMPEDE.
Published in:
JNCI Cancer Spectrum, 2022, v. 6, n. 4, p. 1, doi. 10.1093/jncics/pkac044
By:
- Gong, Jun;
- Posadas, Edwin M
Publication type:
Article
Frontiers in prostate cancer. Telomeres and chaos.
Published in:
Cancer (0008543X), 1995, v. 75, n. S7, p. 2027, doi. 10.1002/1097-0142(19950401)75:7+<2027::AID-CNCR2820751645>3.0.CO;2-6
By:
- Sommerfeld, Hans J.;
- Meeker, Alan K.;
- Posadas, Edwin M.;
- Coffey, Donald S.
Publication type:
Article
A cisplatin conjugate with tumor cell specificity exhibits antitumor effects in renal cancer models.
Published in:
BMC Cancer, 2023, v. 23, n. 1, p. 1, doi. 10.1186/s12885-023-10878-3
By:
- Mrdenovic, Stefan;
- Wang, Yanping;
- Yin, Lijuan;
- Chu, Gina Chia-Yi;
- Ou, Yan;
- Lewis, Michael S.;
- Heffer, Marija;
- Posadas, Edwin M.;
- Zhau, Haiyen E.;
- Chung, Leland W. K.;
- Edderkaoui, Mouad;
- Pandol, Stephen J.;
- Wang, Ruoxiang;
- Zhang, Yi
Publication type:
Article
High-Purity Prostate Circulating Tumor Cell Isolation by a Polymer Nanofiber-Embedded Microchip for Whole Exome Sequencing.
Published in:
Advanced Materials, 2013, v. 25, n. 21, p. 2897, doi. 10.1002/adma.201205237
By:
- Zhao, Libo;
- Lu, Yi-Tsung;
- Li, Fuqiang;
- Wu, Kui;
- Hou, Shuang;
- Yu, Juehua;
- Shen, Qinglin;
- Wu, Dongxia;
- Song, Min;
- OuYang, Wei-Han;
- Luo, Zheng;
- Lee, Tom;
- Fang, Xiaohong;
- Shao, Chen;
- Xu, Xun;
- Garcia, Mitch A.;
- Chung, Leland W. K.;
- Rettig, Matthew;
- Tseng, Hsian-Rong;
- Posadas, Edwin M.
Publication type:
Article
Tumor Cell Isolation: High-Purity Prostate Circulating Tumor Cell Isolation by a Polymer Nanofiber-Embedded Microchip for Whole Exome Sequencing (Adv. Mater. 21/2013).
Published in:
Advanced Materials, 2013, v. 25, n. 21, p. 2870, doi. 10.1002/adma.201370136
By:
- Zhao, Libo;
- Lu, Yi-Tsung;
- Li, Fuqiang;
- Wu, Kui;
- Hou, Shuang;
- Yu, Juehua;
- Shen, Qinglin;
- Wu, Dongxia;
- Song, Min;
- OuYang, Wei-Han;
- Luo, Zheng;
- Lee, Tom;
- Fang, Xiaohong;
- Shao, Chen;
- Xu, Xun;
- Garcia, Mitch A.;
- Chung, Leland W. K.;
- Rettig, Matthew;
- Tseng, Hsian-Rong;
- Posadas, Edwin M.
Publication type:
Article
Circulating monocytes from prostate cancer patients promote invasion and motility of epithelial cells.
Published in:
Cancer Medicine, 2018, v. 7, n. 9, p. 4639, doi. 10.1002/cam4.1695
By:
- Cavassani, Karen A.;
- Meza, Rebecca J.;
- Habiel, David M.;
- Chen, Jie‐Fu;
- Montes, Alexander;
- Tripathi, Manisha;
- Martins, Gislâine A.;
- Crother, Timothy R.;
- You, Sungyong;
- Hogaboam, Cory M.;
- Bhowmick, Neil;
- Posadas, Edwin M.
Publication type:
Article
A prospective analysis of imatinib-induced c-kit modulation in ovarian cancer: A phase II clinical study with proteomic profiling.
Published in:
Cancer (0008543X), 2007, v. 110, n. 2, p. 309, doi. 10.1002/cncr.22757
By:
- Edwin M. Posadas;
- Virginia Kwitkowski;
- Herbert L. Kotz;
- Virginia Espina;
- Lori Minasian;
- Nana Tchabo;
- Ahalya Premkumar;
- Mahrukh M. Hussain;
- Richard Chang;
- Seth M. Steinberg;
- Elise C. Kohn
Publication type:
Article
A phase II and pharmacodynamic study of gefitinib in patients with refractory or recurrent epithelial ovarian cancer.
Published in:
2007
By:
- Posadas, Edwin M;
- Liel, Meghan S;
- Kwitkowski, Virginia;
- Minasian, Lori;
- Godwin, Andrew K;
- Hussain, Mahrukh M;
- Espina, Virginia;
- Wood, Bradford J;
- Steinberg, Seth M;
- Kohn, Elise C
Publication type:
journal article
A phase II and pharmacodynamic study of gefitinib in patients with refractory or recurrent epithelial ovarian cancerThis is a US government work and, as such, is in the public domain in the United States of America.
Published in:
Cancer (0008543X), 2007, v. 109, n. 7, p. 1323, doi. 10.1002/cncr.22545
By:
- Edwin M. Posadas;
- Meghan S. Liel;
- Virginia Kwitkowski;
- Lori Minasian;
- Andrew K. Godwin;
- Mahrukh M. Hussain;
- Virginia Espina;
- Bradford J. Wood;
- Seth M. Steinberg;
- Elise C. Kohn
Publication type:
Article
Stromal epigenetic alterations drive metabolic and neuroendocrine prostate cancer reprogramming.
Published in:
2018
By:
- Mishra, Rajeev;
- Haldar, Subhash;
- Placencio, Veronica;
- Madhav, Anisha;
- Rohena-Rivera, Krizia;
- Agarwal, Priyanka;
- Duong, Frank;
- Angara, Bryan;
- Tripathi, Manisha;
- Zhenqiu Liu;
- Gottlieb, Roberta A.;
- Wagner, Shawn;
- Posadas, Edwin M.;
- Bhowmick, Neil A.;
- Liu, Zhenqiu
Publication type:
journal article
RNA Biomarkers: Glycan Stimulation Enables Purification of Prostate Cancer Circulating Tumor Cells on PEDOT NanoVelcro Chips for RNA Biomarker Detection (Adv. Healthcare Mater. 3/2018).
Published in:
Advanced Healthcare Materials, 2018, v. 7, n. 3, p. 1, doi. 10.1002/adhm.201870013
By:
- Shen, Mo‐Yuan;
- Chen, Jie‐Fu;
- Luo, Chun‐Hao;
- Lee, Sangjun;
- Li, Cheng‐Hsuan;
- Yang, Yung‐Ling;
- Tsai, Yu‐Han;
- Ho, Bo‐Cheng;
- Bao, Li‐Rong;
- Lee, Tien‐Jung;
- Jan, Yu Jen;
- Zhu, Ya‐Zhen;
- Cheng, Shirley;
- Feng, Felix Y.;
- Chen, Peilin;
- Hou, Shuang;
- Agopian, Vatche;
- Hsiao, Yu‐Sheng;
- Tseng, Hsian‐Rong;
- Posadas, Edwin M.
Publication type:
Article
Glycan Stimulation Enables Purification of Prostate Cancer Circulating Tumor Cells on PEDOT NanoVelcro Chips for RNA Biomarker Detection.
Published in:
Advanced Healthcare Materials, 2018, v. 7, n. 3, p. 1, doi. 10.1002/adhm.201700701
By:
- Shen, Mo‐Yuan;
- Chen, Jie‐Fu;
- Luo, Chun‐Hao;
- Lee, Sangjun;
- Li, Cheng‐Hsuan;
- Yang, Yung‐Ling;
- Tsai, Yu‐Han;
- Ho, Bo‐Cheng;
- Bao, Li‐Rong;
- Lee, Tien‐Jung;
- Jan, Yu Jen;
- Zhu, Ya‐Zhen;
- Cheng, Shirley;
- Feng, Felix Y.;
- Chen, Peilin;
- Hou, Shuang;
- Agopian, Vatche;
- Hsiao, Yu‐Sheng;
- Tseng, Hsian‐Rong;
- Posadas, Edwin M.
Publication type:
Article
Saracatinib as a metastasis inhibitor in metastatic castration-resistant prostate cancer: A University of Chicago Phase 2 Consortium and DOD/PCF Prostate Cancer Clinical Trials Consortium Study.
Published in:
Prostate, 2016, v. 76, n. 3, p. 286, doi. 10.1002/pros.23119
By:
- Posadas, Edwin M.;
- Ahmed, Rafi S.;
- Karrison, Theodore;
- Szmulewitz, Russell Z.;
- O'Donnell, Peter H.;
- Wade, James L.;
- Shen, James;
- Gururajan, Murali;
- Sievert, Margarit;
- Stadler, Walter M.
Publication type:
Article
Niraparib with androgen receptor-axis-targeted therapy in patients with metastatic castration-resistant prostate cancer: safety and pharmacokinetic results from a phase 1b study (BEDIVERE).
Published in:
2021
By:
- Saad, Fred;
- Chi, Kim N.;
- Shore, Neal D.;
- Graff, Julie N.;
- Posadas, Edwin M.;
- Lattouf, Jean-Baptiste;
- Espina, Byron M.;
- Zhu, Eugene;
- Yu, Alex;
- Hazra, Anasuya;
- De Meulder, Marc;
- Mamidi, Rao N. V. S.;
- Bradic, Branislav;
- Francis, Peter;
- Hayreh, Vinny;
- Rezazadeh Kalebasty, Arash
Publication type:
journal article
ONECUT2 acts as a lineage plasticity driver in adenocarcinoma as well as neuroendocrine variants of prostate cancer.
Published in:
Nucleic Acids Research, 2024, v. 52, n. 13, p. 7740, doi. 10.1093/nar/gkae547
By:
- Qian, Chen;
- Yang, Qian;
- Rotinen, Mirja;
- Huang, Rongrong;
- Kim, Hyoyoung;
- Gallent, Brad;
- Yan, Yiwu;
- Cadaneanu, Radu M;
- Zhang, Baohui;
- Kaochar, Salma;
- Freedland, Stephen J;
- Posadas, Edwin M;
- Ellis, Leigh;
- Di Vizio, Dolores;
- Morrissey, Colm;
- Nelson, Peter S;
- Brady, Lauren;
- Murali, Ramachandran;
- Campbell, Moray J;
- Yang, Wei
Publication type:
Article
Circulating Tumor Cells in Prostate Cancer: Beyond Enumeration.
Published in:
Clinical Advances in Hematology & Oncology, 2017, v. 15, n. 1, p. 63
By:
- Jie-Fu Chen;
- Yi-Tsung Lu;
- Cheng, Shirley;
- Hsian-Rong Tseng;
- Figlin, Robert A.;
- Posadas, Edwin M.
Publication type:
Article
Is computed tomography a necessary part of a metastatic evaluation for castration-resistant prostate cancer? Results from the Shared Equal Access Regional Cancer Hospital Database.
Published in:
2016
By:
- Hanyok, Brian T.;
- Howard, Lauren E.;
- Amling, Christopher L.;
- Aronson, William J.;
- Cooperberg, Matthew R.;
- Kane, Christopher J.;
- Terris, Martha K.;
- Posadas, Edwin M.;
- Freedland, Stephen J.
Publication type:
journal article
Subclassification of prostate cancer circulating tumor cells by nuclear size reveals very small nuclear circulating tumor cells in patients with visceral metastases.
Published in:
Cancer (0008543X), 2015, v. 121, n. 18, p. 3240, doi. 10.1002/cncr.29455
By:
- Chen, Jie‐Fu;
- Ho, Hao;
- Lichterman, Jake;
- Lu, Yi‐Tsung;
- Zhang, Yang;
- Garcia, Mitch A.;
- Chen, Shang‐Fu;
- Liang, An‐Jou;
- Hodara, Elisabeth;
- Zhau, Haiyen E.;
- Hou, Shuang;
- Ahmed, Rafi S.;
- Luthringer, Daniel J.;
- Huang, Jiaoti;
- Li, Ker‐Chau;
- Chung, Leland W. K.;
- Ke, Zunfu;
- Tseng, Hsian‐Rong;
- Posadas, Edwin M.
Publication type:
Article
Fyn: a novel molecular target in cancer.
Published in:
2010
By:
- Saito YD;
- Jensen AR;
- Salgia R;
- Posadas EM;
- Saito, Yoshihito D;
- Jensen, Ana R;
- Salgia, Ravi;
- Posadas, Edwin M
Publication type:
journal article
A Novel Molecular Target in Cancer.
Published in:
Cancer (0008543X), 2010, v. 116, n. 7, p. 1629, doi. 10.1002/cncr.24879
By:
- Saito, Yoshihito D.;
- Jensen, Ana R.;
- Salgia, Ravi;
- Posadas, Edwin M.
Publication type:
Article
Disparities in Cancer Care and the Asian American Population.
Published in:
Oncologist, 2021, v. 26, n. 6, p. 453, doi. 10.1002/onco.13748
By:
- Lee, Richard J.;
- Madan, Ravi A.;
- Kim, Jayoung;
- Posadas, Edwin M.;
- Yu, Evan Y.
Publication type:
Article
An Open Label Phase Ib Dose Escalation Study of TRC105 (Anti‐Endoglin Antibody) with Axitinib in Patients with Metastatic Renal Cell Carcinoma.
Published in:
Oncologist, 2019, v. 24, n. 2, p. 202, doi. 10.1634/theoncologist.2018-0299
By:
- Choueiri, Toni K.;
- Michaelson, M. Dror;
- Posadas, Edwin M.;
- Sonpavde, Guru P.;
- McDermott, David F.;
- Nixon, Andrew B.;
- Liu, Yingmiao;
- Yuan, Zhenhua;
- Seon, Ben K.;
- Walsh, Meghara;
- Jivani, Manoj A.;
- Adams, Bonne J.;
- Theuer, Charles P.
Publication type:
Article
Circulating Fatty Objects and Their Preferential Presence in Pancreatic Cancer Patient Blood Samples.
Published in:
Frontiers in Physiology, 2022, v. 13, p. 1, doi. 10.3389/fphys.2022.827531
By:
- Wang, Ruoxiang;
- Nissen, Nicholas N.;
- Zhang, Yi;
- Shao, Chen;
- Chu, Chia-Yi;
- Huynh, Carissa;
- Posadas, Edwin M.;
- Tomlinson, James S.;
- Lewis, Michael S.;
- Pandol, Stephen J.
Publication type:
Article
A practical guide for assessing and managing cardiovascular risk during androgen‐deprivation therapy in patients with prostate cancer.
Published in:
Cancer (0008543X), 2024, v. 130, n. 11, p. 1916, doi. 10.1002/cncr.35285
By:
- Solanki, Aum J.;
- Kamrava, Mitchell;
- Posadas, Edwin M.;
- Freedland, Stephen J.;
- Ballas, Leslie;
- Sandler, Howard M.;
- Bairey Merz, C. Noel;
- Atkins, Katelyn M.;
- Nikolova, Andriana P.
Publication type:
Article
Loss of testosterone impairs anti-tumor neutrophil function.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-15397-4
By:
- Markman, Janet L.;
- Porritt, Rebecca A.;
- Wakita, Daiko;
- Lane, Malcolm E.;
- Martinon, Daisy;
- Noval Rivas, Magali;
- Luu, Michael;
- Posadas, Edwin M.;
- Crother, Timothy R.;
- Arditi, Moshe
Publication type:
Article

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