We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
A case of medulloblastoma in adult patient affected by anaplastic oligoastrocytoma.
- Authors
Simonetti, G.; Gaviani, Paola; Lamperti, E.; Innocenti, A.; Botturi, A.; Saini, M.; Pollo, B.; Silvani, A.
- Abstract
Medulloblastomas and high-grade gliomas (HGG) are two distinct brain tumor, with different peculiarities in terms of age of onset, localizations and prognosis. The coexistence of the two neoplasms in the same adult patient is an extremely rare event. We present the case of a woman treated with radio-chemotherapy for an HGG, who developed a cerebellar medulloblastoma 7 years later. Considering the poor prognosis of these tumors, the lack of knowledge about the mechanisms of onset as well as effective therapies, it is necessary to determine the exact role of irradiation and the presence of any potential molecular genetic abnormalities in the developing of the two tumors.
- Subjects
MEDULLOBLASTOMA; BRAIN tumors; CHEMORADIOTHERAPY; GENETIC disorders; PROGNOSIS; THERAPEUTICS
- Publication
Neurological Sciences, 2016, Vol 37, Issue 10, p1727
- ISSN
1590-1874
- Publication type
journal article
- DOI
10.1007/s10072-016-2640-8