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- Title
Systemic lupus erythematosus induced by interferon β1 therapy in a patient with multiple sclerosis.
- Authors
Bahri, Dalila Mrabet; Khiari, Hela; Essouri, Asma; Laadhar, Lilia; Zaraa, Ines; Mrabet, Amel; Meddeb, Nihel; Sellami, Slaheddine
- Abstract
Drug-induced lupus erythematosus is defined as a lupus-like syndrome temporally related to a drug exposure. We report a 34-year-old woman with multiple sclerosis who developed, while being treated with interferon β-1a, myalgia and associated with wrist synovitis. Clinical and immunologic investigations were in favor of systemic lupus erythematosus. Interferon therapy was maintained. Under corticosteroids and antipaludeen treatment, the patient did not develop any other lupic manifestations.
- Subjects
CASE studies; MULTIPLE sclerosis; INTERFERONS; SYNOVITIS; ADRENOCORTICAL hormones; PATIENTS
- Publication
Fundamental & Clinical Pharmacology, 2012, Vol 26, Issue 2, p210
- ISSN
0767-3981
- Publication type
Article
- DOI
10.1111/j.1472-8206.2011.00929.x