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- Title
Risk factors for unexplained recurrent spontaneous abortion in a population from southern China
- Authors
Zhang, Bi-Yun; Wei, Yi-Sheng; Niu, Jian-Min; Li, Yi; Miao, Zhu-Lin; Wang, Zi-Neng
- Abstract
<bold>Objective: </bold>To determine risk factors for recurrent spontaneous abortion (RSA) in women from southern China.<bold>Method: </bold>We looked for associations between RSA and body mass index (BMI), family history of spontaneous abortion, smoking, exposure to environmental tobacco smoke (ETS [also known as passive smoking]), and alcohol and coffee consumption using an unconditional logistic regression model involving 326 patients with RSA and 400 controls.<bold>Results: </bold>Whereas smoking, alcohol consumption, and coffee consumption were not associated with increased risk of RSA, both short (<1 hour/day) and long (> or =1 hour/day) periods of ETS were associated (adjusted odds ratio [OR], 2.30; 95% confidence interval [CI], 1.50-3.52 and adjusted OR, 4.75; 95% CI, 3.23-6.99, respectively). The increased risk of RSA was significant for participants with a BMI of 24.0 or greater (adjusted OR, 1.54; 95% CI, 1.12-2.14) and those with a family history of miscarriage (adjusted OR, 2.12; 95% CI, 1.28-3.49).<bold>Conclusion: </bold>We found ETS, a higher BMI, and a family history of RSA to be independent risk factors for RSA in our population.
- Subjects
CHINA; RISK factors in miscarriages; BODY mass index; WOMEN'S tobacco use; PREGNANT women; ALCOHOL drinking; LOGISTIC regression analysis; DISEASE relapse; PASSIVE smoking; TOBACCO smoke pollution; CAFFEINE; COMPARATIVE studies; RESEARCH methodology; MEDICAL cooperation; RESEARCH; SMOKING; EVALUATION research; CASE-control method; RECURRENT miscarriage
- Publication
International Journal of Gynecology & Obstetrics, 2010, Vol 108, Issue 2, p135
- ISSN
0020-7292
- Publication type
journal article
- DOI
10.1016/j.ijgo.2009.09.019