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- Title
Synthesis of microencapsulated oyster peptides and its effect on inflammatory cytokines and enzyme levels in mice.
- Authors
Zhang, Xiaokui; Zhang, Li; Xu, Minqiu; Li, Qian; Miao, Rongkun
- Abstract
The aim of this study was to investigate the effects of the active oyster peptide extract (AOPs) microcapsules formed with microemulsion gelling method, in order to prolong the bioactivity provided by this ingredient. Bioassay and release tests were done on the microencapsulated formulations. The microcapsules obtained were characterised in terms of particle size and morphology, DSC, FTIR, encapsulation efficiency (EE) and release studies. The particle size and EE of AOPs microcapsules with an loading capacity of about 18.29 % (wt%) ranged from 0.77 to 5.33 µm, and 71.46 to 75.37 %, respectively. The sustained release was observed in simulated intestinal fluid. The release behaviour of microspheres conformed best to Ritger-Peppas model (R = 0.98). For inflammatory cytokine, AOPs microcapsules was shown to effectively attenuated the IL-1β and TNF-α, increased the levels of ACP and lysozyme.
- Publication
Journal of Food Measurement & Characterization, 2017, Vol 11, Issue 2, p610
- ISSN
2193-4126
- Publication type
Article
- DOI
10.1007/s11694-016-9429-6