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- Title
Oral and maxillofacial tuberculosis: A systematic review.
- Authors
de Farias Gabriel, Amanda; Kirschnick, Laura Borges; Só, Bruna Barcelos; Schuch, Lauren Frenzel; Silveira, Felipe Martins; Martins, Marco Antonio Trevizani; Wagner, Vivian Petersen; Lopes, Márcio Ajudarte; Martins, Manoela Domingues
- Abstract
Objectives: This study aimed to analyze the demographic, clinical, histopathological, diagnosis, treatment, and follow‐up data on the occurrence of oral and maxillofacial tuberculosis (OMTB). Methods: Electronic searches without publication date restrictions were undertaken in four databases. Case reports and case series describing the occurrence of OMTB were included. Critical evaluation of studies was done using the Joanna Briggs Institute – University of Adelaide tool for case reports or case series. Results: A total of 217 studies were included in the qualitative synthesis, for a total of 301 cases of OMTB. Of these patients, 192 (63.7%) were male, with an average age of 39.6 ± 19.8 (15 months to 81 years). The tongue (n = 80/26.6%) represented the most common affected site, followed by the mandible (n = 43/14.3%). The clinical presentation consisted mainly of a painful ulcerated lesion (n = 156/56.5%). Histopathological analysis showed a granulomatous inflammation in most cases (n = 156/63.1%). The main diagnostic methods used were sputum test (n = 53/26.8%), culture (n = 49/24.7%) and purified protein derivative (PPD), or Mantoux test (n = 49/24.7%). Antituberculosis therapy was used in 244 cases (100.0%) and 5.2% of patients died. Conclusions: This systematic review provided clinical, demographic data and information about diagnostic methods of OMTB lesions and served as an important guide to assist health professionals in the early diagnosis of these lesions.
- Subjects
ORAL disease diagnosis; TUBERCULOSIS diagnosis; TUBERCULOSIS treatment; ONLINE information services; MEDICAL information storage &; retrieval systems; SYSTEMATIC reviews; MAXILLA; TUBERCULOSIS; DESCRIPTIVE statistics; RESEARCH funding; MEDLINE; EARLY diagnosis; SYMPTOMS
- Publication
Oral Diseases, 2023, Vol 29, Issue 7, p2483
- ISSN
1354-523X
- Publication type
Article
- DOI
10.1111/odi.14290