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- Title
Lasers, stem cells, and COPD.
- Authors
Feng Lin; Josephs, Steven F.; Alexandrescu, Doru T.; Ramos, Famela; Bogin, Vladimir; Gammill, Vincent; Dasanu, Constantin A.; de Necochea-Campion, Rosalia; Patel, Amit N.; Carrier, Ewa; Koos, David R.
- Abstract
The medical use of low level laser (LLL) irradiation has been occurring for decades, primarily in the area of tissue healing and inflammatory conditions. Despite little mechanistic knowledge, the concept of a non-invasive, nonthermal intervention that has the potential to modulate regenerative processes is worthy of attention when searching for novel methods of augmenting stem cell-based therapies. Here we discuss the use of LLL irradiation as a "photoceutical" for enhancing production of stem cell growth/chemoattractant factors, stimulation of angiogenesis, and directly augmenting proliferation of stem cells. The combination of LLL together with allogeneic and autologous stem cells, as well as post-mobilization directing of stem cells will be discussed.
- Subjects
LASERS; STEM cells; OBSTRUCTIVE lung diseases; IRRADIATION; INFLAMMATION; WOUND healing; REGENERATION (Biology)
- Publication
Journal of Translational Medicine, 2010, Vol 8, p1
- ISSN
1479-5876
- Publication type
Article