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- Title
Microenvironment: partners in crime.
- Authors
Legg, Katrin
- Abstract
The article discusses a study that examines how caveolin 1 (CAV1) that is expressed by stromal cells can promote tumour cell migration by remodelling the microenvironment. The study focuses on the role of CAV1 in the surrounding stromal cells. It also revealed that CAV1-associated tumour cell development showed an increased potential for metastasis.
- Subjects
MESENCHYMAL stem cells; TUMOR genetics; ONCOGENES; CANCER genetics; METASTASIS; CANCER invasiveness; CARCINOGENESIS
- Publication
Nature Reviews Cancer, 2011, Vol 11, Issue 9, p624
- ISSN
1474-175X
- Publication type
journal article
- DOI
10.1038/nrc3123