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- Title
Mitochondrial ATP-independent chaperones.
- Authors
Petrakis, Nikos; Alcock, Felicity; Tokatlidis, Kostas
- Abstract
Mitochondria possess a dedicated-chaperone system in the intermembrane space, the small Tims that are ubiquitous in all eukaryotes from yeast to man. They escort membrane proteins to the outer or the inner membrane for proper insertion. These mitochondrial chaperones do not require external energy to perform their function and have structural similarities to other ATP-independent chaperones. Here, we discuss their structural properties and how these relate to their chaperoning function in the mitochondrial intermembrane space. © 2009 IUBMB IUBMB Life 61(9): 909–914, 2009
- Subjects
MITOCHONDRIA; ORGANELLES; PROTEINS; BIOLOGICAL membranes; BIOLOGY
- Publication
IUBMB Life, 2009, Vol 61, Issue 9, p909
- ISSN
1521-6543
- Publication type
Article
- DOI
10.1002/iub.235