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- Title
Patch Testing with a New Composition of Mercapto Mix: A Multicentre Study by the Swedish Contact Dermatitis Research Group.
- Authors
ENGFELDT, Malin; ISAKSSON, Marléne; GLAS, Bo; HAGVALL, Lina; LÖFNERTZ PETERSSON, Anna; MATURA, Mihaly; STENBERG, Berndt; SVEDMAN, Cecilia; BRUZE, Magnus
- Abstract
This study investigated whether more patients with contact allergies were detected by patch testing with mercapto mix with a higher concentration of 2-mercaptobenzothiazolinone (MBT) than the commonly used mercapto mix. A total of 3,143 dermatitis patients in 5 Swedish dermatology departments were patch- tested with 3 mercapto test preparations: MBT 2.0% petrolatum (pet.); mercapto mix 2.0% pet.; and mercapto mix 3.5% pet. Positive reactions to these mercapto mixes varied between 0-0.50%, 0-0.93%, and 0-1.4%, respectively, in the 5 centres. Numerically, mercapto mix 3.5% pet. detected all positive patients and more patch-test positive patients than did the 2 other substances, but the difference was not statistically significant. The authors recommend replacing mercapto mix 2.0% pet. in the Swedish baseline series with mercapto mix 3.5% pet., since the latter also detected those patients who would have been missed because MBT 2.0% is not included in the Swedish baseline series.
- Subjects
CONTACT dermatitis; RESEARCH teams; MIXING; DELAYED hypersensitivity
- Publication
Acta Dermato-Venereologica, 2019, Vol 99, Issue 11, p960
- ISSN
0001-5555
- Publication type
Article
- DOI
10.2340/00015555-3249