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- Title
Epstein-Barr virus and human malignancy.
- Authors
Ziegler, John L.; Magrath, Ian T.; Gerber, Paul; Levine, Paul H.; Ziegler, J L; Magrath, I T; Gerber, P; Levine, P H
- Abstract
The association of the Epstein-Barr virus and two human malignancies, Burkitt's lumphoma and nasopharyngeal carcinoma, is reviewed. Seroepidemiologic, virologic, and immunologic evidence is summarized, and several hypotheses regarding a possible etiologic role for the Epstein-Barr virus in these tumors are presented. With our current state of knowledge we cannot conclude that the Ipstein-Barr virus is oncogenic in man, nor can we yet ascertain the biological and clinical significance of its association with Burkitt's lymphoma and nasopharyngeal carcinoma.
- Subjects
EPSTEIN-Barr virus; BURKITT'S lymphoma
- Publication
Annals of Internal Medicine, 1977, Vol 86, Issue 3, p323
- ISSN
0003-4819
- Publication type
journal article
- DOI
10.7326/0003-4819-86-3-323