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- Title
Systemic Lupus Erythematosus Presenting as Corneal Perforation
- Authors
Chen, Hung-Chi Jesse; Cheng, Ju-Chuan; Hsiao, Ching-Hsi; Ma, David Hui-Kang
- Abstract
Abstract: Systemic lupus erythematosus (SLE) is a multisystem, autoimmune disorder that can have numerous ocular manifestations, which may precede or occur upon initial presentation of SLE. We report on a 72-year-old woman with peripheral corneal perforation but without any predisposing factors. SLE was diagnosed because of signs and symptoms such as arthritis, leukopenia, anemia, positive anti-dsDNA antibody, and positive antinuclear antibody (ANA). Systemic therapy with oral hydroxylchloroquine 200 mg daily was prescribed. Therapeutic penetrating keratoplasty with cryopreserved cornea was also performed to repair the perforated cornea. Six months postoperatively, the corneal lesion became scarred and her visual acuity improved from 2/200 to 20/70 without any ocular or systemic recurrence.
- Subjects
AUTOIMMUNE diseases; VASCULAR diseases; COLLAGEN diseases; CUTANEOUS tuberculosis
- Publication
Tzu Chi Medical Journal, 2009, Vol 21, Issue 2, p169
- ISSN
1016-3190
- Publication type
Article
- DOI
10.1016/S1016-3190(09)60032-X