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- Title
Combination of Cladribine Plus Topotecan for Recurrent or Refractory Pediatric Acute Myeloid Leukemia.
- Authors
Inaba, Hiroto; Stewart, Clinton F.; Crews, Kristine P.; Shengping Yang; Pounds, Stanley; Ching-Hon Pui; Rubnftz, Jeffrey E.; Razzouk, Bassem I.; Ribeiro, Raul C.
- Abstract
The article presents a study which evaluates the efficacy of cladribine combined with topotecan when used during the prognosis for patients with recurrent acute myeloid leukemia (AML). It states that cladribine and topotecan were administered on patients in 5 days with evaluated maximum tolerated dose (MTD) and dose-limiting toxicities (DLTs). The study concludes that the combination of cladribine and topotecan was well tolerated by patients and proved as safe alternative treatment.
- Subjects
TOPOTECAN; ACUTE myeloid leukemia; ALTERNATIVE medicine; DRUG efficacy; DISEASE relapse prevention; ACUTE myeloid leukemia treatment; PROGNOSIS
- Publication
Cancer (0008543X), 2010, Vol 116, Issue 1, p98
- ISSN
0008-543X
- Publication type
Article
- DOI
10.1002/cncr.24712