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Development of a new humanized mouse model to study acute inflammatory arthritis.
Published in:
Journal of Translational Medicine, 2012, v. 10, n. 1, p. 190, doi. 10.1186/1479-5876-10-190
By:
- Alexander V Misharin, Alexander V Misharin;
- Haines III., G. Kenneth;
- Rose, Shawn;
- Gierut, Angelical K.;
- Hotchkiss, Richard S.;
- Perlman, Harris
Publication type:
Article
The Sphingosine Kinase 1 Inhibitor, PF543, Mitigates Pulmonary Fibrosis by Reducing Lung Epithelial Cell mtDNA Damage and Recruitment of Fibrogenic Monocytes.
Published in:
International Journal of Molecular Sciences, 2020, v. 21, n. 16, p. 5595, doi. 10.3390/ijms21165595
By:
- Cheresh, Paul;
- Kim, Seok-Jo;
- Huang, Long Shuang;
- Watanabe, Satoshi;
- Joshi, Nikita;
- Williams, Kinola J.N.;
- Chi, Monica;
- Lu, Ziyan;
- Harijith, Anantha;
- Yeldandi, Anjana;
- Lam, Anna P.;
- Gottardi, Cara;
- Misharin, Alexander V.;
- Budinger, G.R. Scott;
- Natarajan, Viswanathan;
- Kamp, David W.
Publication type:
Article
β₂-Adrenergic agonists augment air pollution-induced IL-6 release and thrombosis.
Published in:
2014
By:
- Chiarella, Sergio E;
- Soberanes, Saul;
- Urich, Daniela;
- Morales-Nebreda, Luisa;
- Nigdelioglu, Recep;
- Green, David;
- Young, James B;
- Gonzalez, Angel;
- Rosario, Carmen;
- Misharin, Alexander V;
- Ghio, Andrew J;
- Wunderink, Richard G;
- Donnelly, Helen K;
- Radigan, Kathryn A;
- Perlman, Harris;
- Chandel, Navdeep S;
- Budinger, G R Scott;
- Mutlu, Gökhan M
Publication type:
journal article
β<sub>2</sub>-Adrenergic agonists augment air pollution-induced IL-6 release and thrombosis.
Published in:
Journal of Clinical Investigation, 2014, v. 124, n. 7, p. 2935, doi. 10.1172/JCI75157
By:
- Chiarella, Sergio E.;
- Soberanes, Saul;
- Urich, Daniela;
- Morales-Nebreda, Luisa;
- Nigdelioglu, Recep;
- Green, David;
- Young, James B.;
- Gonzalez, Angel;
- Rosario, Carmen;
- Misharin, Alexander V.;
- Ghio, Andrew J.;
- Wunderink, Richard G.;
- Donnelly, Helen K.;
- Radigan, Kathryn A.;
- Perlman, Harris;
- Chandel, Navdeep S.;
- Scott Budinger, G. R.;
- Mutlu, Gökhan M.
Publication type:
Article
Mapping single-cell data to reference atlases by transfer learning.
Published in:
Nature Biotechnology, 2022, v. 40, n. 1, p. 121, doi. 10.1038/s41587-021-01001-7
By:
- Lotfollahi, Mohammad;
- Naghipourfar, Mohsen;
- Luecken, Malte D.;
- Khajavi, Matin;
- Büttner, Maren;
- Wagenstetter, Marco;
- Avsec, Žiga;
- Gayoso, Adam;
- Yosef, Nir;
- Interlandi, Marta;
- Rybakov, Sergei;
- Misharin, Alexander V.;
- Theis, Fabian J.
Publication type:
Article
Lactate-dependent transcriptional regulation controls mammalian eye morphogenesis.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-39672-2
By:
- Takata, Nozomu;
- Miska, Jason M.;
- Morgan, Marc A.;
- Patel, Priyam;
- Billingham, Leah K.;
- Joshi, Neha;
- Schipma, Matthew J.;
- Dumar, Zachary J.;
- Joshi, Nikita R.;
- Misharin, Alexander V.;
- Embry, Ryan B.;
- Fiore, Luciano;
- Gao, Peng;
- Diebold, Lauren P.;
- McElroy, Gregory S.;
- Shilatifard, Ali;
- Chandel, Navdeep S.;
- Oliver, Guillermo
Publication type:
Article
Impaired Clearance of Influenza A Virus in Obese, Leptin Receptor Deficient Mice Is Independent of Leptin Signaling in the Lung Epithelium and Macrophages.
Published in:
PLoS ONE, 2014, v. 9, n. 9, p. 1, doi. 10.1371/journal.pone.0108138
By:
- Radigan, Kathryn A.;
- Morales-Nebreda, Luisa;
- Soberanes, Saul;
- Nicholson, Trevor;
- Nigdelioglu, Recep;
- Cho, Takugo;
- Chi, Monica;
- Hamanaka, Robert B.;
- Misharin, Alexander V.;
- Perlman, Harris;
- Budinger, G. R. Scott;
- Mutlu, Gökhan M.
Publication type:
Article
The Effect of Rosuvastatin in a Murine Model of Influenza A Infection.
Published in:
PLoS ONE, 2012, v. 7, n. 4, p. 1, doi. 10.1371/journal.pone.0035788
By:
- Radigan, Kathryn A.;
- Urich, Daniela;
- Misharin, Alexander V.;
- Chiarella, Sergio E.;
- Soberanes, Saul;
- Gonzalez, Angel;
- Perlman, Harris;
- Wunderink, Richard G.;
- Budinger, G. R. Scott;
- Mutlu, Gökhan M.
Publication type:
Article
Reproducible Single-Cell Genomic Research in Pulmonary and Critical Care Medicine.
Published in:
2020
By:
- Eickelberg, Oliver;
- Misharin, Alexander V.;
- Sime, Patricia J.
Publication type:
Editorial
Targeting the Myofibroblast in Pulmonary Fibrosis.
Published in:
2018
By:
- Misharin, Alexander V;
- Budinger, G R Scott
Publication type:
Editorial
Tissue-Resident Alveolar Macrophages Reduce Ozone-induced Inflammation via MerTK-mediated Efferocytosis.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2024, v. 70, n. 6, p. 493, doi. 10.1165/rcmb.2023-0390OC
By:
- Guttenberg, Marissa A.;
- Vose, Aaron T.;
- Birukova, Anastasiya;
- Lewars, Kaitlyn;
- Cumming, R. Ian;
- Albright, Michaela C.;
- Mark, Jasper I.;
- Salazar, Claudia J.;
- Swaminathan, Suchitra;
- Yu, Zhan;
- Sokolenko, Yuliana V.;
- Bunyan, Elsie;
- Yaeger, Michael J.;
- Fessler, Michael B.;
- Que, Loretta G.;
- Gowdy, Kymberly M.;
- Misharin, Alexander V.;
- Tighe, Robert M.
Publication type:
Article
A Novel MIP-1--Expressing Macrophage Subtype in BAL Fluid from Healthy Volunteers.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2023, v. 68, n. 2, p. 176, doi. 10.1165/rcmb.2021-0123OC
By:
- Reyfman, Paul A.;
- Malsin, Elizabeth S.;
- Khuder, Basil;
- Joshi, Nikita;
- Gadhvi, Gaurav;
- Flozak, Annette S.;
- Carns, Mary A.;
- Aren, Kathleen;
- Goldberg, Isaac A.;
- Kim, Seokjo;
- Alexander, Michael;
- Sporn, Peter H. S.;
- Misharin, Alexander V.;
- Budinger, G. R. Scott;
- Lam, Anna P.;
- Hinchcliff, Monique;
- Gottardi, Cara J.;
- Winter, Deborah R.
Publication type:
Article
Expression of ACE2—a Key SARS-CoV-2 Entry Factor—Is Not Increased in the Nasal Mucosa of People with Cystic Fibrosis.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2022, v. 67, n. 1, p. 132, doi. 10.1165/rcmb.2021-0341le
By:
- Sala, Marc A.;
- Markov, Nikolay S.;
- Politanska, Yuliya;
- Abdala-Valencia, Hiam;
- Misharin, Alexander V.;
- Jain, Manu
Publication type:
Article
Lung Injury Induces Alveolar Type 2 Cell Hypertrophy and Polyploidy with Implications for Repair and Regeneration.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2022, v. 66, n. 5, p. 564, doi. 10.1165/rcmb.2021-0356OC
By:
- Weng, Anthea;
- Herrerias, Mariana Maciel;
- Watanabe, Satoshi;
- Welch, Lynn C.;
- Flozak, Annette S.;
- Grant, Rogan A.;
- Aillon, Raul Piseaux;
- Dada, Laura A.;
- Seung Hye Han;
- Hinchcliff, Monique;
- Misharin, Alexander V.;
- Budinger, G. R. Scott;
- Gottardi, Cara J.
Publication type:
Article
Age-related Differences in the Nasal Mucosal Immune Response to SARS-CoV-2.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2022, v. 66, n. 2, p. 206, doi. 10.1165/rcmb.2021-0292OC
By:
- Koch, Clarissa M.;
- Prigge, Andrew D.;
- Anekalla, Kishore R.;
- Shukla, Avani;
- Hanh Chi Do Umehara;
- Setar, Leah;
- Chavez, Jairo;
- Abdala-Valencia, Hiam;
- Politanska, Yuliya;
- Markov, Nikolay S.;
- Hahn, Grant R.;
- Heald-Sargent, Taylor;
- Sanchez-Pinto, L. Nelson;
- Muller, William J.;
- Singer, Benjamin D.;
- Misharin, Alexander V.;
- Ridge, Karen M.;
- Coates, Bria M.
Publication type:
Article
Regulator of Cell Cycle Protein (RGCC/RGC-32) Protects against Pulmonary Fibrosis.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2022, v. 66, n. 2, p. 146, doi. 10.1165/rcmb.2021-0022OC
By:
- Luzina, Irina G.;
- Rus, Violeta;
- Lockatell, Virginia;
- Courneya, Jean-Paul;
- Hampton, Brian S.;
- Fishelevich, Rita;
- Misharin, Alexander V.;
- Todd, Nevins W.;
- Badea, Tudor C.;
- Rus, Horea;
- Atamas, Sergei P.
Publication type:
Article
Improving the Quality and Reproducibility of Flow Cytometry in the Lung: An Official American Thoracic Society Workshop Report.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2019, v. 61, n. 2, p. 150, doi. 10.1165/rcmb.2019-0191ST
By:
- Tighe, Robert M.;
- Redente, Elizabeth F.;
- Yen-Rei Yu;
- Herold, Susanne;
- Sperling, Anne I.;
- Curtis, Jeffrey L.;
- Duggan, Ryan;
- Swaminathan, Suchitra;
- Hideki Nakano;
- Zacharias, William J.;
- Janssen, William J.;
- Freeman, Christine M.;
- Brinkman, Ryan R.;
- Singer, Benjamin D.;
- Jakubzick, Claudia V.;
- Misharin, Alexander V.
Publication type:
Article
Lung Interstitial Macrophages: Establishing Identity and Uncovering Heterogeneity.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2017, v. 57, n. 1, p. 7, doi. 10.1165/rcmb.2017-0150ed
By:
- Koch, Clarissa M.;
- Chiu, Stephen F.;
- Misharin, Alexander V.;
- Ridge, Karen M.
Publication type:
Article
Lrp5/β-Catenin Signaling Controls Lung Macrophage Differentiation and Inhibits Resolution of Fibrosis.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2017, v. 56, n. 2, p. 191, doi. 10.1165/rcmb.2016-0147OC
By:
- Sennello, Joseph A.;
- Misharin, Alexander V.;
- Flozak, Annette S.;
- Berdnikovs, Sergejs;
- Cheresh, Paul;
- Varga, John;
- Kamp, David W.;
- Budinger, G. R. Scott;
- Gottardi, Cara J.;
- Lam, Anna P.
Publication type:
Article
Flow Cytometry Reveals Similarities Between Lung Macrophages in Humans and Mice.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2016, v. 54, n. 1, p. 147, doi. 10.1165/rcmb.2015-0147le
By:
- Bharat, Ankit;
- Bhorade, Sangeeta M.;
- Morales-Nebreda, Luisa;
- McQuattie-Pimentel, Alexandra C.;
- Soberanes, Saul;
- Ridge, Karen;
- DeCamp, Malcolm M.;
- Mestan, Karen K.;
- Perlman, Harris;
- Budinger, G. R. Scott;
- Misharin, Alexander V.
Publication type:
Article
Lung-Specific Loss of α3 Laminin Worsens Bleomycin-Induced Pulmonary Fibrosis.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2015, v. 52, n. 4, p. 503, doi. 10.1165/rcmb.2014-0057OC
By:
- Morales-Nebreda, Luisa I.;
- Rogel, Micah R.;
- Eisenberg, Jessica L.;
- Hamill, Kevin J.;
- Soberanes, Saul;
- Nigdelioglu, Recep;
- Monica Chi;
- Takugo Cho;
- Radigan, Kathryn A.;
- Ridge, Karen M.;
- Misharin, Alexander V.;
- Woychek, Alex;
- Hopkinson, Susan;
- Perlman, Harris;
- Mutlu, Gokhan M.;
- Pardo, Annie;
- Selman, Moises;
- Jones, Jonathan C. R.;
- Budinger, G. R. Scott
Publication type:
Article
Flow Cytometric Analysis of Macrophages and Dendritic Cell Subsets in the Mouse Lung.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2013, v. 49, n. 4, p. 503, doi. 10.1165/rcmb.2013-0086MA
By:
- Misharin, Alexander V.;
- Morales-Nebreda, Luisa;
- Mutlu, Gökhan M.;
- Budinger, G. R. Scott;
- Perlman, Harris
Publication type:
Article
Inflammatory pathways are upregulated in the nasal epithelium in patients with idiopathic pulmonary fibrosis.
Published in:
2018
By:
- Sala, Marc A.;
- Balderas-Martínez, Yalbi Itzel;
- Buendía-Roldan, Ivette;
- Abdala-Valencia, Hiam;
- Nam, Kiwon;
- Jain, Manu;
- Bhorade, Sangeeta;
- Bharat, Ankit;
- Reyfman, Paul A.;
- Ridge, Karen M.;
- Pardo, Annie;
- Sznajder, Jacob I.;
- Budinger, G. R. Scott;
- Misharin, Alexander V.;
- Selman, Moises
Publication type:
journal article
Conditional deletion of caspase-8 in macrophages alters macrophage activation in a RIPK-dependent manner.
Published in:
Arthritis Research & Therapy, 2015, v. 17, p. 1, doi. 10.1186/s13075-015-0794-z
By:
- Cuda, Carla M.;
- Misharin, Alexander V.;
- Khare, Sonal;
- Saber, Rana;
- Tsai, FuNien;
- Archer, Amy M.;
- Homan, Philip J.;
- Haines III, G. Kenneth;
- Hutcheson, Jack;
- Dorfleutner, Andrea;
- Budinger, G. R. Scott;
- Stehlik, Christian;
- Perlman, Harris
Publication type:
Article
Distinctive features of severe SARS-CoV-2 pneumonia.
Published in:
2021
By:
- Budinger, G. R. Scott;
- Misharin, Alexander V.;
- Ridge, Karen M.;
- Singer, Benjamin D.;
- Wunderink, Richard G.
Publication type:
journal article
Residual endotoxin induces primary graft dysfunction through ischemia/reperfusion-primed alveolar macrophages.
Published in:
2020
By:
- Akbarpour, Mahzad;
- Lecuona, Emilia;
- Chiu, Stephen F.;
- Qiang Wu;
- Querrey, Melissa;
- Fernandez, Ramiro;
- Núñez-Santana, Félix L.;
- Haiying Sun;
- Ravi, Sowmya;
- Chitaru Kurihara;
- Walter, James M.;
- Joshi, Nikita;
- Ziyou Ren;
- Roberts, Scott C.;
- Hauser, Alan;
- Kreisel, Daniel;
- Wenjun Li;
- Chandel, Navdeep S.;
- Misharin, Alexander V.;
- Mohanakumar, Thalachallour
Publication type:
journal article
Linear ubiquitin assembly complex regulates lung epithelial-driven responses during influenza infection.
Published in:
2020
By:
- Brazee, Patricia L.;
- Morales-Nebreda, Luisa;
- Magnani, Natalia D.;
- Garcia, Joe G. N.;
- Misharin, Alexander V.;
- Ridge, Karen M.;
- Budinger, G. R. Scott;
- Iwai, Kazuhiro;
- Dada, Laura A.;
- Sznajder, Jacob I.;
- Garcia, Joe Gn
Publication type:
journal article
The role of macrophages in the resolution of inflammation.
Published in:
2019
By:
- Satoshi Watanabe;
- Alexander, Michael;
- Misharin, Alexander V.;
- Budinger, G. R. Scott;
- Watanabe, Satoshi
Publication type:
journal article
Spleen-derived classical monocytes mediate lung ischemia-reperfusion injury through IL-1β.
Published in:
2018
By:
- Hsi-Min Hsiao;
- Fernandez, Ramiro;
- Satona Tanaka;
- Wenjun Li;
- Spahn, Jessica H.;
- Stephen Chiu;
- Akbarpour, Mahzad;
- Ruiz-Perez, Daniel;
- Qiang Wu;
- Turam, Cem;
- Scozzi, Davide;
- Tsuyoshi Takahashi;
- Luehmann, Hannah P.;
- Puri, Varun;
- Scott Budinger, G. R.;
- Krupnick, Alexander S.;
- Misharin, Alexander V.;
- Lavine, Kory J.;
- Yongjian Liu;
- Gelman, Andrew E.
Publication type:
journal article
The PYRIN domain-only protein POP3 inhibits ALR inflammasomes and regulates responses to infection with DNA viruses.
Published in:
Nature Immunology, 2014, v. 15, n. 4, p. 343, doi. 10.1038/ni.2829
By:
- Khare, Sonal;
- Ratsimandresy, Rojo A;
- de Almeida, Lúcia;
- Cuda, Carla M;
- Rellick, Stephanie L;
- Misharin, Alexander V;
- Wallin, Melissa C;
- Gangopadhyay, Anu;
- Forte, Eleonora;
- Gottwein, Eva;
- Perlman, Harris;
- Reed, John C;
- Greaves, David R;
- Dorfleutner, Andrea;
- Stehlik, Christian
Publication type:
Article
The PYRIN domain-only protein POP2 inhibits inflammasome priming and activation.
Published in:
Nature Communications, 2017, v. 8, n. 6, p. 15556, doi. 10.1038/ncomms15556
By:
- Ratsimandresy, Rojo A.;
- Chu, Lan H.;
- Khare, Sonal;
- de Almeida, Lucia;
- Gangopadhyay, Anu;
- Indramohan, Mohanalaxmi;
- Misharin, Alexander V.;
- Greaves, David R.;
- Perlman, Harris;
- Dorfleutner, Andrea;
- Stehlik, Christian
Publication type:
Article
Donor pulmonary intravascular nonclassical monocytes recruit recipient neutrophils and mediate primary lung allograft dysfunction.
Published in:
Science Translational Medicine, 2017, v. 9, n. 394, p. 1, doi. 10.1126/scitranslmed.aal4508
By:
- Zhikun Zheng;
- Chiu, Stephen;
- Akbarpour, Mahzad;
- Haiying Sun;
- Reyfman, Paul A.;
- Anekalla, Kishore R.;
- Abdala-Valencia, Hiam;
- Edgren, Daphne;
- Wenjun Li;
- Kreisel, Daniel;
- Korobova, Farida V.;
- Fernandez, Ramiro;
- McQuattie-Pimentel, Alexandra;
- Zhang, Zheng J.;
- Perlman, Harris;
- Misharin, Alexander V.;
- Budinger, G. R. Scott;
- Bharat, Ankit
Publication type:
Article
The Lung Macrophage: A Jack of All Trades.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2011, v. 184, n. 5, p. 497, doi. 10.1164/rccm.201107-1343ED
By:
- MISHARIN, ALEXANDER V.;
- BUDINGER, G. R. Scott;
- PERLMAN, HARRIS
Publication type:
Article
Modeling human influenza infection in the laboratory.
Published in:
Infection & Drug Resistance, 2015, v. 8, p. 311, doi. 10.2147/IDR.S58551
By:
- Radigan, Kathryn A.;
- Misharin, Alexander V.;
- Chi, Monica;
- Budinger, G. R. Scott
Publication type:
Article
ApoE deficiency exacerbates the development and sustainment of a semi-chronic K/BxN serum transfer-induced arthritis model.
Published in:
2016
By:
- Archer, Amy M.;
- Saber, Rana;
- Rose, Shawn;
- Shaffer, Alexander;
- Misharin, Alexander V.;
- Tsai, FuNien;
- Haines III, G. Kenneth;
- Dominguez, Salina;
- Eren, Mesut;
- Vaughan, Douglas E.;
- Cuda, Carla M.;
- Perlman, Harris
Publication type:
journal article
Thyroid Antigens, Not Central Tolerance, Control Responses to Immunization in BALB/c Versus C57BL/6 Mice.
Published in:
Thyroid, 2009, v. 19, n. 5, p. 503, doi. 10.1089/thy.2008.0420
By:
- Alexander V. Misharin;
- Basil Rapoport;
- Sandra M. McLachlan
Publication type:
Article
Lung transplantation for patients with severe COVID-19.
Published in:
Science Translational Medicine, 2020, v. 12, n. 574, p. 1, doi. 10.1126/scitranslmed.abe4282
By:
- Bharat, Ankit;
- Querrey, Melissa;
- Markov, Nikolay S.;
- Kim, Samuel;
- Kurihara, Chitaru;
- Garza-Castillon, Rafael;
- Manerikar, Adwaiy;
- Shilatifard, Ali;
- Tomic, Rade;
- Politanska, Yuliya;
- Abdala-Valencia, Hiam;
- Yeldandi, Anjana V.;
- Lomasney, Jon W.;
- Misharin, Alexander V.;
- Budinger, G. R. Scott
Publication type:
Article
Individual target pharmacokinetic/pharmacodynamic attainment rates among meropenem-treated patients admitted to the ICU with hospital-acquired pneumonia.
Published in:
Journal of Antimicrobial Chemotherapy (JAC), 2022, v. 77, n. 11, p. 2956, doi. 10.1093/jac/dkac245
By:
- Rohani, Roxane;
- Scheetz, Marc H;
- Donnelly, Helen K;
- Donayre, Alvaro;
- Kang, Mengjia;
- Diaz, Estefani;
- Dedicatoria, Kay;
- Hauser, Alan R;
- Ozer, Egon A;
- Nozick, Sophia;
- Qi, Chao;
- Pawlowski, Anna E;
- Neely, Michael N;
- Misharin, Alexander V;
- Wunderink, Richard G;
- Rhodes, Nathaniel J;
- investigators, NU SCRIPT Study;
- NU SCRIPT Study investigators
Publication type:
Article
Impaired phagocytic function in CX3CR1<sup>+</sup> tissue‐resident skeletal muscle macrophages prevents muscle recovery after influenza A virus‐induced pneumonia in old mice.
Published in:
Aging Cell, 2020, v. 19, n. 9, p. 1, doi. 10.1111/acel.13180
By:
- Runyan, Constance E.;
- Welch, Lynn C.;
- Lecuona, Emilia;
- Shigemura, Masahiko;
- Amarelle, Luciano;
- Abdala‐Valencia, Hiam;
- Joshi, Nikita;
- Lu, Ziyan;
- Nam, Kiwon;
- Markov, Nikolay S.;
- McQuattie‐Pimentel, Alexandra C.;
- Piseaux‐Aillon, Raul;
- Politanska, Yuliya;
- Sichizya, Lango;
- Watanabe, Satoshi;
- Williams, Kinola J.N.;
- Budinger, G. R. Scott;
- Sznajder, Jacob I.;
- Misharin, Alexander V.
Publication type:
Article

Found: 39