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- Title
P63 is a p53 homologue required for limb and epidermal morphogenesis.
- Authors
Mills, Alea A.; Zheng, Binhai; Xiao-Jing Wang; Vogel, Hannes; Roop, Dennis R.; Bradley, Allan
- Abstract
Presents research which concluded that the p53 homologue p63 is essential for ectodermal differentiation during embryogenesis in mice. Role of the p53 tumor suppressor; Traits of mice that lack p53; Developmental defects in mice lacking p63 involving limbs, skin, hair follicles, teeth, and mammary glands.
- Subjects
P53 antioncogene; MICE; HOMOLOGY (Biology); MOLECULAR cell differentiation; EMBRYOS; CYTOGENETICS
- Publication
Nature, 1999, Vol 398, Issue 6729, p708
- ISSN
0028-0836
- Publication type
Article
- DOI
10.1038/19531