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- Title
Enzymatic defluorination of fluorinated compounds.
- Authors
Seong, Hyeon Jeong; Kwon, Seong Woo; Seo, Dong-Cheol; Kim, Jin-Hyo; Jang, Yu-Sin
- Abstract
Fluorine-containing compounds are widely used because they have properties required in textiles and coatings for electronic, automotive, and outdoor products. However, fluorinated compounds do not easily break down in nature, which has resulted in their accumulation in the environment as well as the human body. Recently, the enzymatic defluorination of fluorine-containing compounds has gained increasing attention. Here, we review the enzymatic defluorination reactions of fluorinated compounds. Furthermore, we review the enzyme engineering strategies for cleaving C–F bonds, which have the highest dissociation energy found in organic compounds.
- Subjects
COATED textiles; HUMAN ecology; HUMAN body; ORGANIC compounds; FLUORINE compounds; ELECTROTEXTILES
- Publication
Applied Biological Chemistry, 2019, Vol 62, Issue 1, pN.PAG
- ISSN
2468-0834
- Publication type
Article
- DOI
10.1186/s13765-019-0469-6