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- Title
Gold nanoparticle based colorimetric probe for dopamine detection based on the interaction between dopamine and melamine.
- Authors
Chen, Zhengbo; Zhang, Chenmeng; Zhou, Tianhui; Ma, He
- Abstract
We report on a probe for the colorimetric and bare-eye detection of dopamine (DA). The optical effect is based on the finding that DA inhibits the melamine-induced aggregation of red gold nanoparticles (AuNPs) to form blue AuNP clusters. We presume that the aggregation induced by melamine is due to its strong hydrogen-bonding interactions with DA. The color changes can be monitored by spectrophotometry or the bare eye. The probes works over the 33 nM to 3.33 mM DA concentration range, and levels down to 33 nM can be quantified. The nanoprobe was successfully applied to the determination of DA in spiked serum. [Figure not available: see fulltext.]
- Subjects
GOLD nanoparticles; COLORIMETRY; DOPAMINE; CHEMICAL detectors; MELAMINE; METAL clusters; HYDROGEN bonding
- Publication
Microchimica Acta, 2015, Vol 182, Issue 5/6, p1003
- ISSN
0026-3672
- Publication type
Article
- DOI
10.1007/s00604-014-1417-0