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- Title
Impact of cervical lymph node metastasis on transoral surgery for hypopharyngeal squamous cell carcinoma: A retrospective multicenter study.
- Authors
Ushiro, Koji; Watanabe, Yoshiki; Kishimoto, Yo; Kawai, Yoshitaka; Fujimura, Shintaro; Asato, Ryo; Tsujimura, Takashi; Hori, Ryusuke; Kumabe, Yohei; Yasuda, Kaori; Tamaki, Hisanobu; Iki, Takehiro; Kitani, Yoshiharu; Kurata, Keisuke; Kojima, Tsuyoshi; Takata, Kuniaki; Kada, Shinpei; Takebayashi, Shinji; Shinohara, Shogo; Hamaguchi, Kiyomi
- Abstract
Background: Hypopharyngeal carcinoma is likely to spread to the lymph nodes, but there is no established strategy for management in transoral surgery. Methods: We compared oncologic and functional outcomes in a retrospective multicenter study of patients who underwent transoral surgery for hypopharyngeal carcinoma between 2015 and 2021. Results: Two‐hundred and thirty‐two patients were included. Comparing patients with and without adjuvant radiotherapy, 3‐year regional recurrence‐free survival (RRFS) was not significantly different in pN2b and pN2c, but was significantly worse in pN3b without adjuvant radiotherapy. In patients without neck dissection, the 3‐year RRFS was 85.6%, 76.8%, and 70.0% for T1, T2, and T3 primary lesions, respectively, and was significantly worse for T2 or higher (p = 0.035). Conclusions: In the absence of extracapsular invasion, regional control did not deteriorate without adjuvant therapy. If prophylactic neck dissection is not performed, careful follow‐up is necessary if the primary lesion is T2 or greater.
- Subjects
LYMPHATIC metastasis; SQUAMOUS cell carcinoma; RETROSPECTIVE studies; NECK dissection; SURGERY; MOHS surgery
- Publication
Head & Neck, 2024, Vol 46, Issue 8, p1913
- ISSN
1043-3074
- Publication type
Article
- DOI
10.1002/hed.27666