We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Local recurrence and metachronous multiple cancers after transoral nonrobotic surgery for pharyngeal and laryngeal squamous cell carcinoma: A retrospective multicenter study.
- Authors
Ushiro, Koji; Watanabe, Yoshiki; Kishimoto, Yo; Kawai, Yoshitaka; Fujimura, Shintaro; Asato, Ryo; Tsujimura, Takashi; Hori, Ryusuke; Kumabe, Yohei; Yasuda, Kaori; Tamaki, Hisanobu; Iki, Takehiro; Kitani, Yoshiharu; Kurata, Keisuke; Kojima, Tsuyoshi; Takata, Kuniaki; Kada, Shinpei; Takebayashi, Shinji; Shinohara, Shogo; Hamaguchi, Kiyomi
- Abstract
Background: Late laryngopharyngeal cancers after transoral surgery include not only local recurrences but also metachronous multiple cancers. Methods: We compared clinical information, surgical outcomes, and late laryngopharyngeal cancers in patients who underwent transoral nonrobotic surgery for laryngopharyngeal squamous cell carcinoma without lymph node metastases between 2015 and 2021 in a multicenter retrospective study. Results: Four hundred and fifty‐seven patients were included. Positive surgical margins were found in 121 patients (26.5%). Twenty‐two patients (4.8%) received additional treatment. Positive horizontal margins of invasive carcinoma (p = 0.003) and positive horizontal margins of carcinoma in situ only (p = 0.032) were independent risk factors for local recurrence, and prior radiotherapy (p = 0.001) for metachronous multiple cancers. Local control was significantly worse without additional treatment (p = 0.049), but there was no significant difference in survival. Conclusions: Patients with positive margins had an increased frequency of local recurrence, but salvage therapy was effective.
- Subjects
SQUAMOUS cell carcinoma; SURGICAL margin; RECTAL surgery; LYMPHATIC metastasis; CARCINOMA in situ; RETROSPECTIVE studies
- Publication
Head & Neck, 2024, Vol 46, Issue 1, p118
- ISSN
1043-3074
- Publication type
Article
- DOI
10.1002/hed.27564