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- Title
Efecto del bypass gástrico en el síndrome metabólico y en el riesgo cardiovascular.
- Authors
Ocón J; García B; Benito P; Gimeno S; García R; López P; Ocón Bretón, Julia; García, B; Benito, P; Gimeno, S; García, R; López, P
- Abstract
<bold>Background: </bold>Obesity is associated with increased morbimortality cardiovascular. Individual with metabolic syndrome (MS) are a high risk of developing cardiovascular disease (CVD). The aim of this study was to determine the prevalence of the MS in morbidly obese patients enrolling in a bariatric surgery program and to evaluate the impact of weigh loss induced by gastric bypass on the MS and on the predicted 10-year cardiovascular risk.<bold>Material and Methods: </bold>We studied 46 morbidly obese patients who underwent laparoscopic gastric bypass and were followed for 2 years. MS was defined following the IDF 2005 criteria and the insulin resistance (IR) was calculated by using HOMA index. Risk assessment for estimating 10-year ECV risk was carried out according to Framingham score.<bold>Results: </bold>Before surgery, 67.2% of patients had IR and 60,9% met the definition of the MS. 17.3% of patients had an elevated cardiovascular risk category. 2 years after gastric bypass, the percentage of excess body weight lost was 72%. All patients restored their HOMA index and only 1 patient (3.6%) had MS. Resolution of hypertension, disglucemia and dislipemia has been observed in 85%, 93.8% and 95.6% of patients. Estimated cardiovascular risk decreased from 4.5% at baseline to 1% at 2 years after surgery.<bold>Conclusions: </bold>SM is common in morbidly obese patients. Bypass gastric is associated with an improvement or resolution in cardiovascular risk factors and IR and result in a significant reduction in MS prevalence and of predicted 10-year cardiovascular risk.
- Publication
Nutrición Hospitalaria, 2010, Vol 25, Issue 1, p67
- ISSN
0212-1611
- Publication type
journal article
- DOI
dx.doi.org/S0212-16112010000100010