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Phase 1 pharmacokinetic and safety study of soticlestat in participants with mild or moderate hepatic impairment or normal hepatic function.
Published in:
Pharmacology Research & Perspectives, 2024, v. 12, n. 4, p. 1, doi. 10.1002/prp2.1213
By:
- Yin, Wei;
- Mitra, Pranab;
- Copalu, Veronique;
- Marbury, Thomas C.;
- Rondon, Juan Carlos;
- Lawitz, Eric J.;
- Lloyd, Valerie;
- Baratta, Mike;
- Asgharnejad, Mahnaz;
- Hui, Tom;
- Khan, Yasir
Publication type:
Article
A Phase 1, Single‐Dose Study to Evaluate the Pharmacokinetics and Safety of Bepirovirsen in Adults with Hepatic Impairment and Healthy Participants (B‐Assured).
Published in:
Clinical Pharmacology in Drug Development, 2024, v. 13, n. 10, p. 1088, doi. 10.1002/cpdd.1454
By:
- Noormohamed, Nadia;
- Lukic, Tamara;
- Marbury, Thomas C.;
- Lawitz, Eric J.;
- Prescott, Holly;
- Magee, Mindy;
- Nader, Ahmed;
- Han, Kelong
Publication type:
Article
Interferon γ–Induced Protein10 Kinetics in Treatment-Naive Versus Treatment-Experienced Patients Receiving Interferon-Free Therapy for Hepatitis C Virus Infection: Implications for the Innate Immune Response.
Published in:
Journal of Infectious Diseases, 2014, v. 210, n. 12, p. 1881, doi. 10.1093/infdis/jiu325
By:
- Lin, Jennifer C.;
- Habersetzer, François;
- Rodriguez-Torres, Maribel;
- Afdhal, Nezam;
- Lawitz, Eric J.;
- Paulson, Matthew S.;
- Zhu, Yanni;
- Subramanian, Gangadharan Mani;
- McHutchison, John G.;
- Sulkowski, Mark;
- Wyles, David L.;
- Schooley, Robert T.
Publication type:
Article
CONTROL: A randomized phase 2 study of obeticholic acid and atorvastatin on lipoproteins in nonalcoholic steatohepatitis patients.
Published in:
Liver International, 2019, v. 39, n. 11, p. 2082, doi. 10.1111/liv.14209
By:
- Pockros, Paul J.;
- Fuchs, Michael;
- Freilich, Bradley;
- Schiff, Eugene;
- Kohli, Anita;
- Lawitz, Eric J.;
- Hellstern, Paul A.;
- Owens‐Grillo, Janet;
- Van Biene, Courtney;
- Shringarpure, Reshma;
- MacConell, Leigh;
- Shapiro, David;
- Cohen, David E.
Publication type:
Article
Long‐term follow‐up of clinical trial patients treated for chronic HCV infection with daclatasvir‐based regimens.
Published in:
Liver International, 2018, v. 38, n. 5, p. 821, doi. 10.1111/liv.13596
By:
- Reddy, K. Rajender;
- Pol, Stanislas;
- Thuluvath, Paul J.;
- Kumada, Hiromitsu;
- Toyota, Joji;
- Chayama, Kazuaki;
- Levin, James;
- Lawitz, Eric J.;
- Gadano, Adrian;
- Ghesquiere, Wayne;
- Gerken, Guido;
- Brunetto, Maurizia R.;
- Peng, Cheng‐yuan;
- Silva, Marcelo;
- Strasser, Simone I.;
- Heo, Jeong;
- Mcphee, Fiona;
- Liu, Zhaohui;
- Yang, Rong;
- Linaberry, Misti
Publication type:
Article
Short-duration treatment for chronic hepatitis C virus with daclatasvir, asunaprevir, beclabuvir and sofosbuvir ( FOURward study).
Published in:
Liver International, 2017, v. 37, n. 6, p. 836, doi. 10.1111/liv.13335
By:
- Sulkowski, Mark S.;
- Flamm, Steve;
- Kayali, Zeid;
- Lawitz, Eric J.;
- Kwo, Paul;
- McPhee, Fiona;
- Torbeyns, Anne;
- Hughes, Eric A.;
- Swenson, Eugene S.;
- Yin, Philip D.;
- Linaberry, Misti
Publication type:
Article
Low-density lipoprotein and other predictors of response with telaprevir-based therapy in treatment-experienced HCV genotype 1 patients: REALIZE study.
Published in:
Liver International, 2015, v. 35, n. 2, p. 448, doi. 10.1111/liv.12703
By:
- Berg, Thomas;
- Andreone, Pietro;
- Pol, Stanislas;
- Roberts, Stuart;
- Younossi, Zobair;
- Diago, Moises;
- Lawitz, Eric J.;
- Focaccia, Roberto;
- Foster, Graham R.;
- Horban, Andrzej;
- Lonjon ‐ Domanec, Isabelle;
- DeMasi, Ralph;
- Picchio, Gaston;
- Luo, Donghan;
- De Meyer, Sandra;
- Zeuzem, Stefan
Publication type:
Article
Resistance Analysis of a 3-Day Monotherapy Study with Glecaprevir or Pibrentasvir in Patients with Chronic Hepatitis C Virus Genotype 1 Infection.
Published in:
Viruses (1999-4915), 2018, v. 10, n. 9, p. 462, doi. 10.3390/v10090462
By:
- Ng, Teresa I.;
- Pilot-Matias, Tami;
- Tripathi, Rakesh;
- Schnell, Gretja;
- Krishnan, Preethi;
- Reisch, Thomas;
- Beyer, Jill;
- Dekhtyar, Tatyana;
- Irvin, Michelle;
- Lu, Liangjun;
- Asatryan, Armen;
- Campbell, Andrew;
- Yao, Betty;
- Lovell, Sandra;
- Mensa, Federico;
- Lawitz, Eric J.;
- Kort, Jens;
- Collins, Christine
Publication type:
Article
Infections During Peginterferon/Ribavirin Therapy Are Associated With the Magnitude of Decline in Absolute Lymphocyte Count: Results of the IDEAL Study.
Published in:
Clinical Infectious Diseases, 2014, v. 58, n. 7, p. 960, doi. 10.1093/cid/ciu009
By:
- Melia, Michael T.;
- Bräu, Norbert;
- Poordad, Fred;
- Lawitz, Eric J.;
- Shiffman, Mitchell L.;
- McHutchison, John G.;
- Muir, Andrew J.;
- Galler, Greg W.;
- Nyberg, Lisa M.;
- Lee, William M.;
- Schiff, Eugene;
- Long, Jianmin;
- Noviello, Stephanie;
- Brass, Clifford A.;
- Pedicone, Lisa D.;
- Sulkowski, Mark S.
Publication type:
Article
Pharmacokinetics, safety, and tolerability of BMS‐986263, a lipid nanoparticle containing HSP47 siRNA, in participants with hepatic impairment.
Published in:
CTS: Clinical & Translational Science, 2023, v. 16, n. 10, p. 1791, doi. 10.1111/cts.13581
By:
- Qosa, Hisham;
- de Oliveira, Claudia H. M. C.;
- Cizza, Giovanni;
- Lawitz, Eric J.;
- Colletti, Nicholas;
- Wetherington, Jeffrey;
- Charles, Edgar D.;
- Tirucherai, Giridhar S.
Publication type:
Article
The accuracy of the report of hepatic steatosis on ultrasonography in patients infected with hepatitis C in a clinical setting: A retrospective observational study.
Published in:
BMC Gastroenterology, 2005, v. 5, p. 14, doi. 10.1186/1471-230X-5-14
By:
- Hepburn, Matthew J;
- Vos, Jeffrey A;
- Fillman, Eric P;
- Lawitz, Eric J
Publication type:
Article
Seroprevalence of hepatitis C and associated risk factors among an urban population in Haiti.
Published in:
BMC Gastroenterology, 2004, v. 4, p. 31, doi. 10.1186/1471-230X-4-31
By:
- Hepburn, Matthew J.;
- Lawitz, Eric J.
Publication type:
Article
Efficacy and safety of a two‐drug direct‐acting antiviral agent regimen ruzasvir 180 mg and uprifosbuvir 450 mg for 12 weeks in adults with chronic hepatitis C virus genotype 1, 2, 3, 4, 5 or 6.
Published in:
Journal of Viral Hepatitis, 2019, v. 26, n. 9, p. 1127, doi. 10.1111/jvh.13132
By:
- Lawitz, Eric;
- Gane, Edward;
- Feld, Jordan J.;
- Buti, Maria;
- Foster, Graham R.;
- Rabinovitz, Mordechai;
- Burnevich, Eduard;
- Katchman, Helena;
- Tomasiewicz, Krzysztof;
- Lahser, Fred;
- Jackson, Beth;
- Shaughnessy, Melissa;
- Klopfer, Stephanie;
- Yeh, Wendy W.;
- Robertson, Michael N.;
- Hanna, George J.;
- Barr, Eliav;
- Platt, Heather L.;
- Gordon, Stuart C.;
- Lawitz, Eric J.
Publication type:
Article
Response-guided therapy in patients with genotype 1 hepatitis C virus: Current status and future prospects.
Published in:
Journal of Gastroenterology & Hepatology, 2014, v. 29, n. 8, p. 1574, doi. 10.1111/jgh.12632
By:
- Lawitz, Eric J;
- Membreno, Fernando E
Publication type:
Article
A Pilot Study of Interleukin-11 in Subjects with Chronic Hepatitis C and Advanced Liver Disease Nonresponsive to Antiviral Therapy.
Published in:
American Journal of Gastroenterology (Springer Nature), 2004, v. 99, n. 12, p. 2359, doi. 10.1111/j.1572-0241.2004.40047.x
By:
- Lawitz, Eric J.;
- Hepburn, Matthew J.;
- Casey, Thomas J.
Publication type:
Article

Found: 15