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- Title
Effect of Nitrogen Mustard on Erythrocyte Acetylcholinesterase.
- Authors
VINCENT, P. C.; BRITTLE, NEA; REEVE, T. S.
- Abstract
NITROGEN mustard (HN2) is known to inactivate certain enzymes, particularly hexokinases and phosphatases1, in addition to the better-known effects on nucleic acids common to all alkylating agents1-5. In the course of examining the effects of nitrogen mustard on circulating erythrocytes, it became important to assay its effect, if any, on erythrocyte acetylcholinesterase. This enzyme is located on the red cell surface, accessible to trypsin inactivation6.
- Publication
Nature, 1963, Vol 200, Issue 4911, p1110
- ISSN
0028-0836
- Publication type
Article
- DOI
10.1038/2001110a0